{"product_id":"revvity-nex352050uc","title":"Revvity, NEX352050UC, α-MSH, Nle , D-Phe , [ I], 50µCi","description":"\u003cp\u003eOverview\u003cbr\u003e\n50 µCi Quantities of α-MSH, Nle4, D-Phe7, [125I] are available for your research.\u003cbr\u003e\nWe offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.\u003cbr\u003e\nRadiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.\u003cbr\u003e\nReferences for NEX352:\u003c\/p\u003e\n\n\u003cp\u003eConde-Frieboes, K., Thøgersen, H., Lau, J.F., Sensfuss, U., Hansen, T.K., Christensen, L., Spetzler, J., Olsen, H.B., Nilsson, C., Raun, K., Dahl, K., Hansen, B.S., Wulff, B.S. (2012), Identification and in vivo and in vitro characterization of long acting and melanocortin 4 receptor (MC4-R) selective α-melanocyte-stimulating hormone (α-MSH) analogues. J Med Chem, 55 (5): 1969-1977.\u003cbr\u003e\nVagner, J., Handl, H.L., Gillies, R.J., Hruby, V.J. (2004), Novel targeting strategy based on multimeric ligands for drug delivery and molecular imaging: homooligomers of alpha-MSH. Bioorg Med Chem Lett, 14 (1): 211-215. Molecular Weight-~1770\u003cbr\u003e\nSpecific Activity-2200 Ci\/mmol  (81.4 TBq\/mmol)\u003cbr\u003e\nCAS Number-75921-69-6\u003c\/p\u003e\n\n\u003cp\u003eApplication-Drug Discovery \u0026amp; Development\u003cbr\u003e\nBrand-NEN Radiochemicals\u003cbr\u003e\nBuffer\/Solvent-0.08M Tris HCl, 0.08M NaCl, 0.05M ßmercaptoethanol, 0.25% BSA, 50 KIU\/ml Trasylol®, (pH 8.5): ethanol (5:1)\u003cbr\u003e\nDetection Modality-Radiometric\u003cbr\u003e\nFresh Lot Days-Third Monday of each month\u003cbr\u003e\nLabel Position-Nominally Labeled\u003cbr\u003e\nPackaging-NENSure vial\u003cbr\u003e\nRadioisotope-125 I\u003cbr\u003e\nReceptor-Melanocortin\u003cbr\u003e\nShipping Information-Shipped on Dry Ice\u003cbr\u003e\nShipping Conditions-Shipped in Dry Ice\u003cbr\u003e\nSpecial Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.\u003cbr\u003e\nStorage Conditions--20°C\u003cbr\u003e\nTherapeutic Area-CNS \u0026amp; Neurologic Inflammation Metabolic Disorders Pain\u003cbr\u003e\nUnit Size-50 µCi\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46774565732521,"sku":"NEX352050UC","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-nex352050uc","provider":"Iright","version":"1.0","type":"link"}