{"product_id":"revvity-nova-802500","title":"Revvity, NOVA-802500, NEXTFLEX Cas9-gRNA Globin Depletion Enzyme (Human)","description":"\u003cp\u003eOverview\u003cbr\u003e\nGlobin transcripts can account for a large fraction of reads in whole blood RNA sequencing libraries, which can mask low-abundance, biologically relevant transcripts. The NEXTFLEX Cas9-gRNA Globin Depletion Enzyme (Human) is a cost-effective, workflow-independent, and highly specific enzyme that reduces globin-derived reads, so more sequencing capacity is directed toward informative genes, without requiring you to move to a new library prep kit.\u003cbr\u003e\nIt uses a DASH-style (Depletion of Abundant Sequences by Hybridization) CRISPR-Cas9 depletion approach, with a precomplexed Cas9 and pool of guides that cleave human globin genes at any dsDNA stage. Whether you use your own prep method or a commercial kit, this module gives you clean, reproducible depletion of globin sequences and improved coverage of non-globin transcripts.\u003c\/p\u003e\n\n\u003cp\u003eCas9-gRNA-mediated targeted removal of human globin genes\u003cbr\u003e\nReady-to-use: provided as a Cas9-gRNA complex with integrated RNase inhibitor and 10X Cas9 Buffer\u003cbr\u003e\nFast: short one-hour reaction time with only 5 minutes of hands-on time\u003cbr\u003e\nConvenient: easily fits into any library prep workflow\u003cbr\u003e\nFlexible: compatible with short- and long-read sequencing\u003cbr\u003e\nAutomation-compatible: easily incorporated into manual or automated workflows Automation Compatible-Yes\u003cbr\u003e\nProduct Group-RNA Depletion\u003cbr\u003e\nShipping Conditions-Shipped in Dry Ice\u003cbr\u003e\nUnit Size-250 μL\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775358390441,"sku":"NOVA-802500","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-nova-802500","provider":"Iright","version":"1.0","type":"link"}