ÄKTA readyflux TFF system 500
ÄKTA readyflux™ filtration systems are fully automated tangential flow filtration (TFF) solutions that combine single-use flow kits and intuitive software to streamline bioprocessing workflows. Here’s what you can expect:
• No programming required
Easily create and run methods with intuitive UNICORN™ software featuring pre-defined phases — no coding or programming skills needed.
• Quick system reconfiguration
Choose from multiple systems and single-use flow kit sizes to match your process scale. Install kits quickly to reduce batch turnaround time and cleanroom downtime.
• Compact, efficient design
Achieve high concentration factors and maximize product recovery with a low minimum recirculation volume.
• Broad filtration compatibility
Use with both filter cassettes and hollow fiber cartridges, supporting microfiltration and ultrafiltration/diafiltration (UF/DF) applications and enabling flexibility.
• Closed-system operation
Maintain sterility and containment when paired with ReadyMate™ flow kits and ReadyMate™ or AseptiQuik™ connectors, ensuring process integrity.
• Plays well with others
Integrate with multiple mixers to increase capacity or with other single-use equipment such as upstream bioreactors or downstream chromatography systems for enhanced process connectivity and control.
Compare ÄKTA readyflux™ systems
System |
ÄKTA readyflux™ TFF system 500 |
ÄKTA readyflux™ |
ÄKTA readyflux™ XL |
Flow rate |
5 – 500 mL/min |
0.1 – 18 L/min |
5 – 60 L/min |
Recirculation tank |
1 L |
50 – 200 L
(Xcellerex™ XDUO mixer connected through PROFIBUS) |
50 – 500 L
(Xcellerex™ XDUO mixer connected through PROFIBUS) |
ReadyCircuit™ 2-D Hanging Pillow Bag |
N/A |
1 – 20 L |
N/A |
Filters |
Hollow fiber filter cartridge size |
0.0016 – 0.029 m²
(up to 2 cartridges/system) |
4, 5, 6, 8, 9
(up to 2 cartridges/system) |
35, 45, 55, 65
(up to 4 cartridges/system) |
Filter cassettes, total filter area |
0.001 – 0.1 m² |
0.1 – 2.5* m² |
1.0 – 10* m² |
* Filter area based on a feed flow of 6-8 L/min/m 2
Explore the ÄKTA readyflux™ in 3D |
Watch ÄKTA readyflux™ video tutorial series Flow kits The flow kits include a single-use pump head and tubing, as well as integrated sensors for pressure, conductivity, temperature, flow, UV, and pH (depending on the flow kit; see ordering information for details). Flow kits are available with Tri-Clamp connectors or with ReadyMate™ or AseptiQuik™ connectors for aseptic connection, depending on the system requirements. All flow kits are gamma irradiated. Flow kits with ReadyMate™ connectors are supplied with a sterile claim.
Visit product page for the flow kits System software UNICORN™ software provides intuitive and flexible method creation, system control, and process evaluation to simplify your filtration workflows. The software includes four integrated modules: Method Editor: provides a user-friendly interface to easily create or modify methods. System Control: enables performing and monitoring runs in real time. Evaluation: facilitates comprehensive data analysis and automated report generation. Administration: manages user access, system logs, and built‑in SQL Server™ database tools. Visit the
product page for UNICORN™ software to learn more.