Agilent, 5190-2403, Agilent Bio MAb, NP3, 4.5 x 50 mm

Agilent Bio MAb, NP3, 4.5 x 50 mm. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations.

Specifications:
Brand: Agilent Bio MAb
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteinsmAbs
Particle Size: 3 µm
Particle Type: Non-porous
Phase: WCX
Pressure Rating: 551 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

**********The following product description is generated by AI and is for reference only. If you have any questions, please contact customer service.**********
This high-performance chromatography column is engineered for robust and efficient analysis of monoclonal antibodies and related large biomolecules. It features a non-porous particle design (NP3) and precise dimensions of 4.5 x 50 mm, delivering excellent resolution, reproducibility, and rapid separation for protein characterization workflows. Ideal for reversed-phase applications, the column supports critical quality attribute assessment, charge variant analysis, and protein purity evaluation in both research and biopharmaceutical development.

Its non-porous surface ensures minimized sample adsorption, making it suitable for high-sensitivity detection with minimal carryover. The column is optimized for use with Agilent HPLC and UHPLC systems, including the 1260 Infinity II and 1290 Infinity series. Flexibility in method development is supported, and it is fully compatible with standard 3.0 mm or 4.6 mm ID LC systems. Typical usage scenarios include the quantitation of monoclonal antibody variants, aggregated forms, and fragment analysis in regulated or discovery environments.

This column also integrates effectively with Agilent’s range of bioinert flow paths and is complemented by Agilent protein standards, mobile phases, and sample handling solutions, enabling comprehensive protein analytics from method development through to routine QC testing.