Agilent, 5190-2543, Agilent Bio SEC-5, 2000Å, 4.6 x 300 mm, 5 µm

Agilent Bio SEC-5, 2000Å, 4.6 x 300 mm, 5 µm. A size exclusion column for aggregate analysis of very large biological molecules. Resolving range 150 kDa to >10 MDa.

Specifications:
Brand: Agilent Bio SEC-5
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 300 mm
Maximum Temperature: 80 °C
Molecular Weight Upper Limit: > 10,000,000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 5 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 2000 Å
Pressure Rating: 240 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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The Agilent Bio SEC-5 column with a 2000Å pore size, dimensions of 4.6 x 300 mm, and 5 µm particle size is engineered for high-resolution size exclusion chromatography of biomolecules. This column delivers superior separation of proteins, antibodies, and other large macromolecules, making it ideal for characterization and purity assessment in biopharmaceutical research and quality control. Its robust silica-based design ensures consistent performance, reproducibility, and long column life, even under demanding analytical conditions.

Optimized for aqueous mobile phases, the column effectively handles sensitive biological samples while minimizing non-specific interactions. It is especially well-suited for analyzing high molecular weight proteins and protein complexes, aggregate content, and molecular size distribution studies. Researchers benefit from its compatibility with a range of Agilent LC systems, including the 1260 Infinity II and 1290 Infinity II series, as well as multiple third-party liquid chromatography systems. The column is also fully supported by Agilent’s portfolio of SEC standards and mobile phases, allowing seamless integration into existing workflows. This product is a trusted solution for laboratories focused on biotherapeutic development, protein characterization, and advanced life science research seeking reliable and precise size-based separation.