Agilent, 799775-944, AdvanceBio RP-mAb Diphenyl, 2.1 x 50 mm, 3.5 µm

AdvanceBio RP-mAb Diphenyl, 2.1 x 50 mm, 3.5 µm. A reversed-phase diphenyl HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins when alternate selectivity is needed or preferred.

Specifications:
Brand: AdvanceBio RP mAb Diphenyl
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: Diphenyl
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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The AdvanceBio RP-mAb Diphenyl column, featuring dimensions of 2.1 x 50 mm and a particle size of 3.5 micrometers, is engineered for high-resolution reversed-phase separations of monoclonal antibodies and related biotherapeutics. Utilizing a unique diphenyl stationary phase, this column enhances selectivity and peak shape for both intact proteins and subunit analysis. Its robust performance supports applications in method development, quality control, and detailed characterization of monoclonal antibody heterogeneity, including glycoform and clip variant profiling. The column is optimized for use with UHPLC and HPLC systems, including Agilent 1290 Infinity, 1260 Infinity, and comparable platforms from other major manufacturers. AdvanceBio RP-mAb columns are suitable for researchers working in biopharmaceutical development, process monitoring, and regulatory compliance, providing reproducible and reliable results with minimal sample carryover. For optimal results, the column can be used with Agilent AdvanceBio Sample Prep and BioInert LC systems, as well as paired with mass spectrometry for sensitive detection and identification. This product supports rapid, accurate reversed-phase separations, accelerating workflows in antibody research, development, and quality assurance.