Agilent, 884973-902, ZORBAX GF-450, 9.4 x 250 mm, 6 µm

ZORBAX GF-450, 9.4 x 250 mm, 6 µm. These legacy USP L35 zirconium-stabilized silica-based SEC columns have a pore size of 300 Å to separate proteins ranging from 10 to 900 kDa molecular weight.

Specifications:
Brand: ZORBAX
Hardware: SS
Inner Diameter (ID): 9.4 mm
LC Platform: Preparative HPLC
Length: 250 mm
Maximum Temperature: 60 °C
Molecular Weight Lower Limit: 10000 Da
Molecular Weight Upper Limit: 900000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisPeptidesProteins
Particle Size: 6 µm
Particle Type: Fully Porous
Phase: GF-450
Pore Size: 300 Å
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 3-8.5

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The ZORBAX GF-450 is an advanced size exclusion chromatography (SEC) column designed for high-resolution separation of biomolecules, including proteins, peptides, and other macromolecules. Featuring a 9.4 x 250 mm dimension and 6 micron particle size, this column delivers excellent efficiency and robust performance for analytical and preparative workflows. It is especially suited for research in molecular weight determination, aggregate and oligomer analysis, and purity assessment in biopharmaceutical development.

Engineered for compatibility with common HPLC systems, including Agilent 1100, 1200, and 1260 Infinity series, the column integrates seamlessly into existing laboratory setups. The proprietary silica-based packing ensures consistent results, minimal sample interaction, and optimal flow characteristics, supporting both routine and advanced biomolecular characterization.

Typical usage scenarios include protein purification, quality control, and characterization of antibody constructs or therapeutic proteins. Researchers benefit from reproducible separations under gentle, native conditions, safeguarding the integrity of delicate macromolecules. The GF-450 model aligns with other columns in the ZORBAX GF series, allowing method flexibility and scalability. Overall, this column offers reliable performance for laboratories involved in pharmaceuticals, biotechnology, and structural biology, ensuring confidence in critical macromolecular analyses.