Agilent, PL1245-1102, PL-SCX 1000Å, 25 x 50 mm, 10 µm

PL-SCX 1000Å, 25 x 50 mm, 10 µm. A strong cation exchange HPLC prep column with fully porous PS/DVB particles. This column can withstand a wide pH range (1-14) and is stable at elevated temperatures.

Specifications:
Brand: PL-SCX
Hardware: SS
Inner Diameter (ID): 25 mm
LC Platform: Preparative HPLC
Length: 50 mm
Maximum Temperature: 80 °C
Part Number Application: Proteins
Part Number Application Domain: Biopharma
Particle Size: 10 µm
Particle Type: Fully Porous
Phase: SCX
Pore Size: 1000 Å
Pressure Rating: 207 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: 0.1M Sodium Sulfate
Technique: LC
UNSPSC Code: 41115711
pH Range: 1-14

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Designed for high-resolution ion-exchange chromatography, this strong cation exchange (SCX) column features a 1000 angstrom pore size and a 10 micron particle size, optimized within a 25 x 50 mm dimension. Utilizing a robust polymeric resin, this product delivers consistent and reliable separation of peptides, proteins, and other charged biomolecules, particularly for applications involving complex biological samples. Its large pore structure ensures enhanced capacity and efficient analyte interaction, making it ideal for the purification and characterization of high molecular weight compounds.

This column is routinely employed in proteomics research, pharmaceutical development, and quality control laboratories, supporting diverse separation workflows including peptide mapping and impurity profiling. The design allows for streamlined integration with common HPLC and UHPLC systems from Agilent as well as other major manufacturers. Compatibility with a range of mobile phases provides operational flexibility, while its chemical stability ensures longevity over repeated uses.

The column is recommended for researchers seeking robust, reproducible separations in both analytical and preparative scale workflows. For expanded capabilities or method development, it can be paired with other Agilent polymer-based columns or ion-exchange chemistries to tailor selectivity and optimize resolution for complex sample matrices.