Agilent, PL1812-3102, PLRP-S 1000Å, 100 x 300 mm, 30 µm

PLRP-S 1000Å, 100 x 300 mm, 30 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 100 mm
LC Platform: Preparative HPLC
Length: 300 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: PeptidesPreparative HPLC Columns & Bulk MediaProteins
Particle Size: 30 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 1000 Å
Pressure Rating: 103 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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This Agilent column features a 1000 angstrom pore size, dimensions of 100 by 300 millimeters, and 30 micron particle size, making it ideal for high-performance reversed-phase liquid chromatography of large biomolecules such as proteins and peptides. Its polymeric packing material provides exceptional chemical stability across a wide pH range, supporting robust and reproducible separations even under harsh mobile phase conditions. The large pore size accommodates the efficient separation of high molecular weight analytes without sacrificing resolution.

Researchers commonly employ this column in proteomics, biopharmaceutical development, and quality control laboratories to analyze biomolecular therapeutics, monoclonal antibodies, and protein digests. The stationary phase is fully compatible with most analytical and preparative HPLC systems, including Agilent platforms, and can withstand cleaning and regeneration procedures, contributing to extended column lifetimes.

Due to its versatility and durability, the column is suitable for scale-up workflows from method development to process monitoring in both research and production environments. It aligns with related polymeric column products for consistent performance across different scales and complex sample types. This column supports precise, high-capacity biomolecule purification and analysis, addressing evolving challenges in modern life science and pharmaceutical research.