Thermo Fisher, J63397.MB, Geldanamycin, 98+%, Thermo Scientific Chemicals

Thermo Fisher, J63397.
MB, Geldanamycin, 98+%, Thermo Scientific Chemicals Geldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins. It interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
CAS: 30562-34-6
IUPAC Name: 13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.
3.
1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Molecular Formula: C29H40N2O9
InChI Key: QTQAWLPCGQOSGP-UHFFFAOYNA-N
SMILES: COC1CC(C)CC2=C(OC)C(=O)C=C(NC(=O)C(C)=CC=CC(OC)C(OC(N)=O)C(C)=CC(C)C1O)C2=O
Form: Powder or crystals or crystalline powder
Assay from Supplier's CofA: >98.
0% (HPLC)
Appearance (Color): Yellow