Waters, 186000218, Symmetry Shield RP18 Column, 100Å, 5 µm, 4.6 mm X 50 mm, 1/pk

These reversed-phase columns contain Waters patented embedded polar group technology that “shields” the silica’ residual silanol surface from highly basic analytes. The reduced silanol activity for the SymmetryShield RP18 column significantly improves peak shape and resolution.

Specifications
Chemistry: C18
Separation Mode: Reversed Phase
Particle Substrate: Silica
pH Range Min: 2 pH
pH Range Max: 8 pH
Maximum Pressure: 6000 psi (415 Bar)
Endcapped: Yes
Bonding Technology: Shield RP18
Silanol Activity: Low
Particle Shape: Spherical
Particle Size: 5 µm
Endfitting Type: Waters
Pore Size: 100 Å
Format: Column
Surface Area: 335
System: HPLC
USP Classification: L1
Inner Diameter: 4.6 mm
Length: 50 mm
Carbon Load: 17 %
UNSPSC: 41115709
Brand: Symmetry
Product Type: Columns
Units per Package: 1 pk

Additional Information
Symmetry Shield RP18 Column, 100Å, 5 µm, 4.6 mm X 50 mm, 1/pk Deliver consistent, repeatable chromatographic findings throughout the lifespan of a breakthrough pharmaceutical product by using the Symmetry Shield RP18 column. The lab equipment delivers great consistency, making it perfect for applications like developing new analytical techniques for cutting-edge pharmaceutical and biopharmaceutical goods. The analytical column's goal is to reduce the range of possible column specifications so that you can get consistent findings. This is accomplished by making sure that the surface coverage parameters are the strictest in the sector. As a result, there are fewer resolution shifts and more consistent batch-to-batch and column-to-column outcomes. The proprietary embedded polar group technology from Waters is present in the Symmetry Shield RP18 column. The purpose of this method is to "protect" the column's remaining silanol surface from very basic analytes. The Symmetry Shield RP18 column's peak shape and resolution are greatly improved as a result of the decreased silanol activity that results. Superior peak form is achieved across a pH range, thanks to the high bonding density and low residual silanol activity of the packing materials of the Symmetry Shield RP18 column. As a result, you may quickly improve your approach and operate at neutral or low pH levels without having to worry about losing the peak shape. The Symmetry Shield RP18 column possesses silanol activity compared to the conventional C18 and C8 columns, which results in decreased retention for basic chemicals. The Symmetry lab equipment is thus perfectly suited to serve as the leading instrument for method development. We recommend that you also learn more about the Symmetry Shield RP18 VanGuard Cartridge, 100Å, 5 µm, 3.9 mm X 5 mm, 3/pk , and use it in conjunction with the Symmetry column. The cartridge is made using the exact packing materials that are present in the column and thus ideally suited to work with the column. It works by filtering out unwanted contaminants from the mobile stream.

FAQ
What Is The pH Range Offered By The Symmetry Shield RP18 Column? The Waters Symmetry Shield RP18 Column listed here offers an operating pH range of 2-8. What Is The Maximum Pressure That The Waters Symmetry Shield RP18 Column Can Sustain? The Waters Symmetry Shield RP18 Column listed here is able to withstand a maximum of 6,000 psi (415 Bar) pressure.