Thermo Fisher, 22295, AMAS (N-α-maleimidoacet-oxysuccinimide ester)

AMAS (N-α-maleimidoacet-oxysuccinimide ester) Thermo Scientific Pierce AMAS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a very short spacer arm (4.
4 angstroms).
Features of AMAS:
•Reactive groups:NHS esterandmaleimide
•Reactive towards: amino and sulfhydryl groups
• Shortest of aliphatic spacer series which includes AMAS,BMPS,GMBSandEMCS
• NHS ester end couples with primary amines at pH 7-9, forming stable amide bonds
• Maleimide reacts with -SH groups at pH 6.
5-7.
5, forming stable thioether linkages
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Very short aliphatic spacer has low potential for eliciting an immune responseCell Permeability: Yes
Description: AMAS
Form: Powder
Labeling Method: Chemical Labeling
Molecular Weight (g/mol): 252.
18
PEGylated: No
Product Line: Pierce™
Quantity: 50 mg
Reactive Moiety: Maleimide, NHS Ester
Shipping Condition: Ambient
Solubility: DMF, DMSO
Spacer Arm Length: 4.
4 Å
Water Soluble: No
Chemical Reactivity: Amine-Sulfhydryl
Cleavable: No
Crosslinker Type: Heterobifunctional
Format: Standard
Product Type: Crosslinker
Spacer: Short (<10 Å)
Unit Size: Each