SAFC - Merck KGaA Life Science Brand

SAFC is a specialized brand within the life science business of Merck KGaA, Darmstadt, Germany (operating as MilliporeSigma in the US and Canada), dedicated to providing high-quality raw materials, process chemicals, and services for the biopharmaceutical, pharmaceutical, and diagnostics industries.

With decades of experience in GMP manufacturing and regulatory compliance, SAFC supports every stage of drug development and production — from early clinical trials to commercial-scale manufacturing. Its portfolio is designed to meet the highest standards of quality, traceability, and supply chain security, enabling customers to bring safe and effective products to market efficiently.

Core Product Categories

1. Cell Culture Media & Supplements

   • Powder and liquid cell culture media for mammalian, microbial, and insect cells

   • Serum, growth factors, and media supplements

   • Chemically defined and animal component–free (ACF) formulations

2. Process Chemicals & Buffers

   • GMP-grade salts, acids, bases, and solvents

   • Custom buffer and solution preparation services

   • Stabilizers, excipients, and formulation agents for drug products

3. Raw Materials for API and Biologics Manufacturing

   • Specialty reagents for small molecule synthesis

   • Bioprocess raw materials for monoclonal antibodies, vaccines, and cell therapies

   • High-purity chemicals for nucleic acid and protein therapeutics production

4. Custom Manufacturing & Contract Services

   • GMP custom synthesis of small molecules and peptides

   • Custom cell culture media design and scale-up

   • Analytical testing and regulatory documentation support

5. Supply Chain & Quality Management

   • Secure global sourcing and dual-site manufacturing options

   • Comprehensive product documentation, including Certificates of Analysis (CoA) and regulatory dossiers

   • Change notification and risk management programs to ensure consistent supply

In addition to SAFC, Merck’s major life science brands include Sigma-Aldrich (chemicals and reagents), Millipore (filtration and purification), Milli-Q (ultrapure water systems), and Supelco (analytical products).

Our main Merck product collections are available for browsing below. If you require Merck products not listed in these collections, please contact us for a quotation.