Thermo Fisher, 22298, BMPS (N-β-maleimidopropyl-oxysuccinimide ester)

BMPS (N-β-maleimidopropyl-oxysuccinimide ester) Thermo Scientific Pierce BMPS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (5.
9 Å).
Features of BMPS:
•Reactive groups:NHS esterandmaleimide
•Reactive towards: amino and sulfhydryl groups
• C3-homolog of aliphatic spacer series which includesAMAS, BMPS,GMBSandEMCS
• NHS ester end couples with primary amines at pH 7-9, forming stable amide bonds
• Maleimide reacts with -SH groups at pH 6.
5-7.
5, forming stable thioether linkages
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Short aliphatic spacer has low potential for eliciting an immune responseProduct References:Crosslinker Application Guide -- search for recent literature references for this productCell Permeability: Yes
Description: BMPS
Form: Solid
Labeling Method: Chemical Labeling
Molecular Weight (g/mol): 266.
21
PEGylated: No
Product Line: Pierce™
Quantity: 50 mg
Reactive Moiety: Maleimide, NHS Ester
Shipping Condition: Ambient
Solubility: DMF, DMSO
Spacer Arm Length: 5.
9 Å
Water Soluble: No
Chemical Reactivity: Amine-Sulfhydryl
Cleavable: No
Crosslinker Type: Heterobifunctional
Format: Standard
Product Type: Crosslinker
Spacer: Short (<10 Å)
Unit Size: Each