Thermo Fisher, S1531, Succinimidyl 3-(2-Pyridyldithio)Propionate (SPDP)

Succinimidyl 3-(2-Pyridyldithio)Propionate (SPDP) The heterobifunctional, crossslinker succinimidyl3-(2-pyridyldithio)propionate (SPDP)enables one to covalently link two target groups. The succinimidyl ester chemically reacts with primary amines and after mild reduction of the dithiol, it can react form a disulfide with other thiols. Crosslinking reagents are useful for probing the spatial relationships and interactions within and between biomolecules.
Cell Permeability: Yes
Description: SPDP
Form: Solid
Labeling Method: Chemical Labeling
Molecular Weight (g/mol): 312.
36
PEGylated: No
Quantity: 100 mg
Reactive Moiety: NHS Ester, Pyridyldisulfide
Solubility: DMF, DMSO
Spacer Arm Length: 6.
8 Å
Water Soluble: No
Chemical Reactivity: Amine-Sulfhydryl
Cleavable: By Thiols
Crosslinker Type: Heterobifunctional
Format: Standard
Product Type: Crosslinker
Spacer: Short (<10 Å)
Unit Size: Each