Cytiva, 17526902, MabSelect™ Xtra antibody purification chromatography resin

MabSelect Xtra, 200 mL MabSelect Xtra, with extra high dynamic binding capacity, is a protein A resin developed to meet the demands of increasing levels of expression in monoclonal antibody feedstocks. • Higher dynamic binding capacity than currently available Protein A chromatography resins. • Improved process economics through reduced raw materials costs and/or reduced number of cycles. • High purity capture due to high ligand selectivity and matrix hydrophilicity. • Slightly lower pressure/flow properties compared to MabSelect SuRe and MabSelect. • Resin fulfills industrial demands for security of supply, robust performance, and regulatory support. Increased porosity MabSelect Xtra has the same recombinant Protein A ligand as MabSelect but is based on a high-flow agarose base matrix with increased porosity and a slightly decreased particle size compared to MabSelect. This results in higher capacity—MabSelect Xtra has about 30% higher dynamic binding capacity for IgG than currently available Protein A chromatography resins. In addition, MabSelect Xtra has a higher capacity for many Fc-fusion proteins. Lower costs Compared with he other protein A resins, MabSelect Xtra resin provides a lower overall production cost due to the possibility of processing concentrated feedstocks in fewer batches. Prepacked columns and other formats MabSelect Xtra is available in the following formats: Process development scale – prepacked PreDictor MabSelect Xtra filter plates – 96-well plates for high-throughput screening or process development. PreDictor RoboColumn MabSelect Xtra – minitiaturized column format for high throughput process development HiScreen MabSelect Xtra columns – optimized for method and process development. Lab/research scale – prepacked for manual purification HiTrap MabSelect Xtra columns – for easy use with a syringe, peristaltic pump, or chromatography system. Lab/research scale – prepacked for automated purification and analysis HiTrap MabSelect Xtra columns – for easy use with a syringe, peristaltic pump, or chromatography system. Learn about prepacked HiScreen MabSelect Xtra , HiTrap MabSelect Xtra , ReadyToProcess MabSelect Xtra columns , PreDictor MabSelect Xtra or PreDictor Robocolumns MabSelect Xtra