Agilent, 5188-5217, Multiple Affinity Removal Column - Ms-3 (Mouse), 4.6 x 50 mm

Multiple Affinity Removal Column - Ms-3 (Mouse), 4.6 x 50 mm

Specifications:
UNSPSC Code: 41115711

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This high-performance chromatography column is specially designed for the targeted removal of the three most abundant mouse serum proteins—albumin, IgG, and transferrin—thereby enriching low-abundance proteins for more in-depth proteomic analysis. Engineered with advanced affinity resins and a robust 4.6 x 50 mm format, it allows for efficient sample preparation, leading to higher sensitivity and improved reproducibility in downstream LC-MS, 2D-PAGE, and biomarker discovery workflows. By minimizing high-abundance protein interference, researchers can achieve greater accuracy and detection capabilities when characterizing complex mouse plasma and serum samples.

Ideal for pre-fractionation in biomedical, pharmaceutical, and translational research, the column streamlines sample processing before analytical or quantitative mass spectrometry. Its high specificity and capacity enable effective depletion workflows, saving valuable time and resources. This column is fully compatible with Agilent 1100, 1200, 1260, and 1290 series HPLC systems and can be integrated into automated workflows for high-throughput laboratories. Optimized protocols and matching buffer systems are available for seamless operation and reproducibility. The column complements a suite of Agilent sample preparation products, supporting comprehensive proteomic and biomarker studies in mouse models and facilitating reliable data generation in research and development environments.