Thermo Fisher Chemicals Collection — Analytical Solvents, Reagents & CoAs
12634 productsThermo Scientific™ Chemicals (Thermo Fisher Chemicals) brings together trusted lines such as Fisher Chemical, Acros Organics, Alfa Aesar, Maybridge, and Fisher BioReagents to support daily work in analysis, synthesis, and quality control. On this page you can review grades, typical applications, storage notes, and documentation, then reach out for pricing and lead times that fit your project.

Thermo Scientific™ Chemicals Portfolio Overview
Thermo Scientific™ Chemicals covers routine laboratory essentials and highly specialized reagents in one place. You’ll find analytical-grade solvents for HPLC/LC-MS/GC, acids and bases, buffers and salts, organic synthesis building blocks, catalysts and metal salts, bioreagents, and reference standards—designed to streamline selection across your workflows.
What’s included (high-level):
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Analytical solvents: HPLC, LC-MS, and GC grades for low background and consistent retention.
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Acids, bases & buffers: ACS/AR grades for preparation, titration, and pH control.
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Inorganics & salts: High-purity options for assays and buffer makeup.
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Organic reagents: Aldehydes, acids, bases, halides, protecting groups, ligands.
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Metals & catalysts: Precious-metal salts, heterogeneous catalysts, organometallics.
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BioReagents: Electrophoresis and common biochemistry essentials.
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Standards & references: For calibration, method verification, and QC trending.
Grades & Purity: HPLC, LC-MS, GC, ACS/AR
Choosing the correct grade protects method performance and lot-to-lot continuity. Start from the analytical or process requirement, then confirm purity benchmarks and impurity ceilings. Pay attention to UV cutoffs, residue on evaporation, trace metals, water, stabilizers, and plasticizer background depending on your detection method.
Grades at a glance (selection guide):
Grade | Typical use | Key specs to check | Practical note |
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HPLC | Routine LC with UV/FLD | UV absorbance profile, residue on evaporation | Balanced purity and cost for daily analysis |
LC-MS | LC with mass spectrometry | Trace metal limits, background noise, leachables | Minimizes ion suppression and adduct formation |
GC | Gas chromatography | Volatile impurities, water content | Reduces baseline drift, improves peak shape |
ACS / AR | General lab prep | Assay %, specified impurities | Reliable for buffer and reagent makeup |
Anhydrous / Dry | Moisture-sensitive chemistry | Karl Fischer moisture, inhibitor type | Specify packaging (septum/ampule) when needed |
Tip: If you scale a method from R&D to QC, lock the grade early and tie it to documentation (SDS/CoA) to simplify audits and change control.
Applications in Analysis, Synthesis & QC
Different operations have different tolerance for background and impurities. Map the task to the grade, then refine by impurity ceilings. The quick paths below help you narrow candidates before you compare pack sizes and documents.
Analytical testing (chromatography & titration):
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HPLC/LC-MS: Acetonitrile, methanol, water, isopropanol, formic acid, ammonium formate/acetate, trifluoroacetic acid for mobile phases and modifiers.
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GC: Hexane, heptane, toluene, methylene chloride, methanol and GC standards; consider water and volatile impurity limits.
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Wet chemistry: Standardized acids/bases, titrants, indicators, and buffer salts for routine assays.
Organic & inorganic synthesis:
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Reagents & building blocks: Aldehydes, acids, bases, halides, coupling agents, protecting-group reagents.
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Catalysis: Pd, Pt, Rh, Ru salts and supported catalysts; NHC/biaryl phosphine ligands.
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Inorganics/materials: Nitrates, chlorides, carbonates, oxides and metal powders for materials and nanochemistry.
Biochemistry & teaching labs:
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Buffers & media components: Tris, HEPES, phosphate salts, SDS, glycine for electrophoresis and routine prep.
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Stains & standards: Dyes, ladders, and reference materials for method checks and demos.
How to Choose the Right Thermo Scientific Reagent
A consistent selection process prevents rework and supports validation. Begin with the analytical or synthetic goal, then confirm grade, impurity ceilings, packaging, and documents. The checklist below helps you finalize a line-item that your approvers can sign off on.
Selection checklist:
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Define the task: LC-MS method, GC assay, moisture-sensitive coupling, or routine buffer makeup.
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Fix the grade first: HPLC, LC-MS, GC, ACS/AR, or anhydrous; confirm UV cutoff, ROE, or trace metals as relevant.
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Lock documents: Batch-specific CoA and current SDS; add USP/NF/Ph.Eur or REACH statements if required.
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Specify packaging: Bottle vs ampule, septum/AcroSeal-type closures, inhibitor presence, preservative needs.
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Plan logistics: Hazard class, temperature control, and expected lead time to match your schedule.
Popular Categories: Solvents, Acids/Bases, Buffers, Catalysts
Use the groups below to jump directly to the families you purchase most often. Each category can be browsed by grade, pack size, and availability so you can keep methods and stock aligned without overbuying.
Recommended browse paths:
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Analytical Solvents (HPLC / LC-MS / GC) – low background options for chromatography and sample prep.
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Acids, Bases & Salts – ACS/AR grades for titration, pH control, and buffer stock.
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Buffers & Additives – formic/TFA, ammonium salts, phosphate and Tris systems for LC and biochemistry.
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Organic Synthesis Reagents – halides, bases, oxidants/reductants, coupling agents, protecting groups.
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Catalysts & Metal Salts – Pd/Pt/Rh/Ru salts, supported catalysts, and specialty ligands.
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BioReagents Essentials – electrophoresis reagents and common biochemistry components.
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Standards & Reference Materials – calibration and verification materials for QC trending.
Featured Thermo Scientific™ Chemicals SKUs
Below are representative, high-demand Thermo Scientific™/Fisher Chemical™/Fisher BioReagents™ items customers most often shortlist for LC-MS, GC, analytical, and life-science workflows. Each entry includes the verified catalog number, grade, typical pack sizes, and CAS where applicable—so you can shortlist and quote fast.
Catalog No. | Product name | Grade | Typical pack sizes shown by supplier | CAS |
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A955500 | Acetonitrile | Optima™ LC/MS | 500 mL; 1 L; 2.5 L; 4 L | 75-05-8 |
A456500 | Methanol | Optima™ LC/MS | 500 mL; 1 L; 2.5 L; 4 L | 67-56-1 |
W6500 | Water | Optima™ LC/MS | 500 mL; 1 L; 2.5 L; 4 L | 7732-18-5 |
A11705AMP | Formic Acid, 99.0+% | Optima™ LC/MS (ampules/bottles) | 0.5 mL; 1 mL; 2 mL; 10 mL; 50 mL | 64-18-6 |
A11605AMP | Trifluoroacetic Acid (TFA) | Optima™ LC/MS (ampules/bottles) | 0.5 mL; 1 mL; 2 mL; 10 mL; 50 mL | 76-05-1 |
A11550 | Ammonium Formate | Optima™ LC/MS | 50 g (glass bottle) | 540-69-2 |
A11450 | Ammonium Acetate | Optima™ LC/MS | 50 g (glass bottle) | 631-61-8 |
H3074 | Hexanes | GC Resolv™ | 4 L (glass) | 92112-69-1 |
H3604 | n-Heptane, 99% | Optima™ for HPLC & GC | 4 L (amber glass) | 142-82-5 |
BP152500 | Tris base (Trizma®) | Molecular Biology | 500 g; 1 kg; 5 kg; 10 kg; 25 kg | 77-86-1 |
BP310100 | HEPES (free acid) | Molecular Biology | 100 g; 500 g; 1 kg; 5 kg | 7365-45-9 |
BP410500 | HEPES Sodium Salt | Molecular Biology | 500 g; 1 kg; 2.5 kg | 75277-39-3 |
S271500 | Sodium Chloride (crystalline) | Certified ACS | 500 g; 1 kg; 3 kg; 10 kg; 50 kg; 350 lb | 7647-14-5 |
S318-100 | Sodium Hydroxide pellets | Certified ACS | 100 g (series includes 1 kg; 3 kg; 10 kg) | 1310-73-2 |
419355000 | Silver Nitrate, 99+% | ACS reagent | 50 g; 100 g; 250 g; 500 g; 2.5 kg | 7761-88-8 |
AC217085000 | Boric Acid, 99.5% | for analysis (Acros/ Thermo Scientific Chemicals) | 500 g (also 2.5 kg; 10 kg) | 10043-35-3 |
AC389872500 | Sodium Phosphate Monobasic (anhydrous) | for analysis (Acros/ Thermo Scientific Chemicals) | 250 g | 7558-80-7 |
AC207802500 | Sodium Phosphate Monobasic Monohydrate | for analysis (Acros/ Thermo Scientific Chemicals) | 2.5 kg | 10049-21-5 |
011034.18 | Palladium(II) chloride, 99.9% (metals basis) | Thermo Scientific Chemicals (Alfa Aesar legacy) | 50 g (also 10 g; 25 g) | 7647-10-1 |
A12012.18 | Palladium, 10% on carbon, Type 487 (dry) | Thermo Scientific Chemicals (Alfa Aesar legacy) | 2 g; 10 g; 50 g | 7440-05-3 |
FAQs: Grades, SDS/CoA, Storage & Shipping
Short answers below remove friction during purchasing and validation. If your process has additional constraints, include them in your quote request so we can match grade and packaging precisely.
Q1. What’s the practical difference between HPLC and LC-MS grades?
HPLC grade targets low UV background and residue on evaporation; LC-MS grade adds tighter controls on metals, leachables, and background ions to reduce suppression and adducts in MS detection.
Q2. How do I get a specific batch CoA?
When you request a quote or place an order, include the lot requirement or ask for current lots and CoAs. Batch documents are tied to the lot shipped and should be archived with your method files.
Q3. Can I buy the same chemical from 100 mL to multi-liter packs?
Yes. Many solvents and reagents are offered across small-scale and bulk sizes. Choose the smallest pack that minimizes open time if moisture or contamination is a concern.
Q4. How are flammable or corrosive items shipped?
They ship under the relevant hazard class with compliant packaging. Lead times may vary by region and season. If you require temperature control or limited-quantity options, note this in your request.
Q5. Do different closures affect purity over time?
They can. For moisture-sensitive or oxygen-sensitive products, select sealed ampules or septum-equipped closures to reduce ingress. Check labels for inhibitors or stabilizers that protect against degradation.
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