Agilent, 5190-2411, Agilent Bio MAb, NP5, 2.1 x 250 mm, PEEK

Agilent Bio MAb, NP5, 2.1 x 250 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio MAb
Hardware: PEEK
Inner Diameter (ID): 2.1 mm
LC Platform: BioInert
Length: 250 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteinsmAbs
Particle Size: 5 µm
Particle Type: Non-porous
Phase: WCX
Pressure Rating: 413 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio MAb NP5 column, sized 2.1 x 250 mm and constructed with durable PEEK hardware, is a high-performance solution engineered for the analysis of monoclonal antibodies and protein biotherapeutics. Designed with non-porous 5 µm particle technology, this column enables fast, high-resolution separation of large biomolecules, delivering precise and reproducible profiling in SEC and HPLC workflows. Its robust PEEK construction ensures chemical compatibility and minimizes sample adsorption, making it optimal for applications involving sensitive or low-abundance proteins. This column is widely employed in research and quality control laboratories for characterizing molecular weight variants, protein aggregates, and fragments in biopharmaceutical development. It integrates seamlessly with Agilent HPLC and UHPLC systems, including 1260 Infinity II and 1290 Infinity II series, as well as other standard liquid chromatography instruments equipped with compatible column dimensions. Researchers in pharmaceutical, biotechnology, and analytical environments benefit from reliable and accurate data, supporting critical decision-making in product development and manufacturing. The column is a part of Agilent’s comprehensive suite of biocolumns and is compatible with a range of detection methods, including UV and mass spectrometry, providing versatility across various analytical workflows.