Agilent, GX24-401, AdvanceBio Gly-X 2-AB Express labeling module, 24-ct

AdvanceBio Gly-X 2-AB Express labeling module, 24-ct. Utilizes 2-AB (2-aminobenzamide) dye to derivatize released glycans. The proven 2-AB dye assures data continuity for ongoing projects.

Specifications:
Application: Reductive amination 2-AB labeling chemistry without dry down
Count: 24
Deglycosylation Efficiency: > 99 %
Equipment & Reagents Provided by User: Acetonitrile (ACN), MS-grade (Fisher A955-4 recommended), ~4 mL per sampleDI water, ~100 µl per sampleGly-X vacuum manifold spacer and heater block lid (included in GX400 Gly-X 2-AB Express starter kit, or use GX100 spacer and alternate heater lid)Two Thermo Scientific 88871001 Compact dry block heaters with 96 well PCR heat blocks.Two dry block heaters with 96 well PCR heat blocks. One of the heaters can be substituted with a 96-well thermocycler. Denaturation and deglycosylation can be performed using a thermocycler. A heat block is required for the labeling step.Vacuum manifold (Millipore MSVMHTS00)Vacuum pump (Millipore WP6211560, 110 V. WP6122050, 220 V. Welch WOB-L Pump 2522)
Kit Configuration: Sample Prep Module
Label: 2-AB
Prep time (approx): 130 min (24 samples)
Protein Load Range: 1-40 µg
Recovery: > 80 %
Stability: At least 1 month at -20°C, 5 days at 4–8°C
Technique: LC & LC/MS

**********The following product description is generated by AI and is for reference only. If you have any questions, please contact customer service.**********
The AdvanceBio Gly-X 2-AB Express labeling module offers an efficient solution for rapid fluorescent labeling of N-glycans from glycoprotein samples. Designed for up to 24 reactions, this robust kit streamlines workflow by enabling high-throughput sample preparation in under two hours. The included 2-aminobenzamide (2-AB) labeling chemistry ensures sensitive detection and consistent quantitation of released N-glycans, supporting reliable data generation for biopharmaceutical characterization, quality control, and glycoprotein profiling. The kit is optimized for compatibility with Agilent AdvanceBio Glycan Mapping columns and is fully validated for use with UHPLC and HPLC systems equipped with fluorescence detection, including Agilent’s 1260 Infinity II and 1290 Infinity LC platforms. It integrates seamlessly with workflows involving glycoprotein therapeutics, monoclonal antibody analysis, and biosimilar comparability studies. The labeling module is ideal for laboratories seeking reproducibility and high sensitivity in glycan analysis, allowing researchers to accelerate glycoanalytical projects while maintaining confidence in data accuracy. Compatible related products include Agilent glycan release kits and sample preparation accessories, further enabling a complete workflow solution for N-glycan characterization in regulatory and research environments.