Agilent, PL1812-6101, PLRP-S 300Å, 100 x 300 mm, 10 µm

PLRP-S 300Å, 100 x 300 mm, 10 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 100 mm
LC Platform: Preparative HPLC
Length: 300 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: PeptidesPreparative HPLC Columns & Bulk MediaProteins
Particle Size: 10 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 300 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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Engineered for high-performance analytical and preparative liquid chromatography, this reversed phase polymeric column offers robust separations for biomolecules and synthetic polymers. Featuring a 300 angstrom pore size and a 10 micron particle size, the column efficiently handles large proteins, peptides, oligonucleotides, and hydrophobic biomolecules, supporting applications in pharmaceutical development, proteomics, and biotechnology research. Its chemically stable polystyrene-divinylbenzene matrix is ideal for use under extreme pH conditions and elevated temperatures, delivering reproducible results across a range of mobile phases.

The 100 by 300 millimeter dimensions provide substantial loading capacity, suitable for both method development and scale-up purification. The column is compatible with most modern HPLC and UHPLC systems, integrating seamlessly into Agilent and other industry-standard chromatography platforms. Common research applications include protein purification, peptide mapping, aggregate analysis, and high-throughput screening where retention of hydrophobic and high molecular weight analytes is critical. For further workflow optimization, it can be paired with a range of Agilent detectors, pumps, and autosamplers, as well as other PLRP-S column dimensions and cartridge formats to match specific analytical needs. This column is a dependable choice for challenging bioseparation tasks in regulated and research laboratories.