Agilent, PL1980-1250PK, AdvanceBio SEC 120A 1.9um 2.1x50mm PEEK

AdvanceBio SEC 120A 1.9um 2.1x50mm PEEK. A size exclusion column designed for higher resolution and faster separation of protein and peptide aggregates and fragments. PEEK-lined stainless steel hardware offers a metal-free sample flow path.

Specifications:
Brand: AdvanceBio SEC
Guard Column: No
Hardware: PEEK Lined SS
Inner Diameter (ID): 2.1 mm
LC Platform: BioInert
Length: 50 mm
Maximum Temperature: 80 °C (20 to 40 °C recommended)
Molecular Weight Lower Limit: 1000 Da
Molecular Weight Upper Limit: 80000 Da
Particle Size: 1.9 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 120 Å
Pressure Rating: 620 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer/0.02% Sodium azide
Technique: LC & LC/MS
pH Range: 2-8.5

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The AdvanceBio SEC 120A 1.9um 2.1x50mm PEEK column is optimized for high-resolution size exclusion chromatography, designed to deliver superior performance in biomolecule analysis. Featuring advanced 1.9 micron particle technology with a 120 Angstrom pore size, this column enables precise separation of proteins, monoclonal antibodies, and other biologics while maintaining biomolecular integrity. Its compact 2.1 x 50 mm dimensions and durable PEEK hardware support high-throughput workflows and compatibility with both UHPLC and standard LC systems. This product is ideal for applications such as molecular weight determination, aggregate quantification, and quality control in biopharmaceutical development and manufacturing. Researchers benefit from rapid analysis times without compromising resolution, supporting both analytical and process-scale needs. It pairs seamlessly with Agilent’s 1200 Infinity Series LC systems and is fully compatible with a range of bio-inert LC instrumentation. The column integrates well with other AdvanceBio SEC columns to cover various molecular sizes and analytical requirements. Its robust construction minimizes sample interaction with metal surfaces, reducing protein adsorption and ensuring reproducible, reliable results. This high-performance SEC solution supports demanding environments where accurate biomolecule characterization is critical.