Merck, 475828-1MG, β₂-Microglobulin, Human, Recombinant, E. coli

Recombinant, human β₂-microglobulin fused at the N-terminus to a His•Tag sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.