Merck, 20724AST, Astec® CYCLOBOND I 2000 DMP Chiral HPLC Column

The reaction of the 3,5-dimethylphenyl isocyanate with the hydroxyl groups of β-cyclodextrin results in a pi-basic phase similar in character to the naphthylethyl carbamate phases. The selectivity is greater for the CYCLOBOND I 2000 DMP when the chiral center of the analyte is part of a ring structure or is on the α carbon. This phase has been very useful for derivatized amines, like amphetamine ACQ. •Bonded phase: 3,5-Dimethylphenyl carbamate modified β-cyclodextrin