Agilent, 5190-2415, Agilent Bio MAb, NP10, 4.6 x 250 mm, PEEK

Agilent Bio MAb, NP10, 4.6 x 250 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio MAb
Hardware: PEEK
Inner Diameter (ID): 4.6 mm
LC Platform: BioInert
Length: 250 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteinsmAbs
Particle Size: 10 µm
Particle Type: Non-porous
Phase: WCX
Pressure Rating: 275 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio MAb NP10 column offers high-resolution performance for the analysis and characterization of monoclonal antibodies and large biomolecules. Featuring a 4.6 x 250 mm dimension and constructed from robust PEEK material, this column is optimized to ensure excellent chemical compatibility and minimized carryover, supporting both routine and advanced biopharmaceutical workflows. The NP10 stationary phase facilitates efficient size exclusion chromatography, providing precise molecular size discrimination for critical quality attribute assessment, such as aggregation, fragmentation, and variant analysis.

Ideal for use in research, development, and quality control laboratories, this column supports applications including the quantitation and validation of monoclonal antibodies, biosimilars, and therapeutic proteins. Its design ensures reproducible results and extended column lifetime in demanding environments. The column is fully compatible with Agilent InfinityLab and 1100, 1200, and 1260 LC systems, as well as other industry-standard HPLC platforms, ensuring seamless integration into existing workflows. Paired with Agilent’s comprehensive bio-analytical solutions, this column enhances confidence in structural integrity and purity assessments, supporting regulatory compliance and robust product development in the biopharmaceutical industry.