Agilent, 5190-2431, Agilent Bio SCX, NP5, 2.1 x 250 mm, PEEK

Agilent Bio SCX, NP5, 2.1 x 250 mm, PEEK. A strong cation exchange HPLC column with nonporous particles. Particle size is 5 μm. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio SCX
Column Material: PEEK
Hardware: PEEK
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 250 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteins
Particle Size: 5 µm
Particle Type: Non-porous
Phase: SCX
Pressure Rating: 413 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio SCX NP5 column features a 2.1 x 250 mm dimension and is constructed with durable PEEK hardware, making it ideal for high-performance ion exchange chromatography applications. Engineered for superior separation of biomolecules such as proteins, peptides, and other charged analytes, this column utilizes strong cation exchange functionality, supporting high-capacity and efficient resolution even with complex biological samples. The non-porous 5 micron particle technology ensures rapid mass transfer, minimizing peak broadening and delivering sharp, reproducible chromatographic results.

This column is particularly well-suited for the analysis of monoclonal antibodies, evaluation of protein charge variants, and detailed characterization of therapeutic biotherapeutics. Its chemical compatibility and inert construction support use with both traditional and bio-inert UHPLC and HPLC systems, facilitating reliable performance in pharmaceutical, biotechnology, and proteomics research environments. Compatible with a broad range of buffer systems and commonly used in conjunction with Agilent LC systems, it also pairs seamlessly with other bio-friendly columns and components, maximizing workflow versatility. Designed for researchers requiring precise, reproducible biomolecule separations, this column integrates advanced materials and innovative design to ensure robust operation and consistent results in demanding laboratory settings.