Agilent, 5190-2433, Agilent Bio SCX, NP10, 4.6 x 250 mm

Agilent Bio SCX, NP10, 4.6 x 250 mm. A strong cation exchange HPLC column with nonporous particles. Particle size is 10 μm. Nonporous particles are best for efficient mass transfer and high resolution separations.

Specifications:
Brand: Agilent Bio SCX
Column Material: Stainless Steel
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 250 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteins
Particle Size: 10 µm
Particle Type: Non-porous
Phase: SCX
Pressure Rating: 275 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio SCX, NP10, 4.6 x 250 mm is a high-performance strong cation exchange (SCX) liquid chromatography column engineered for exceptional separation of proteins, peptides, and other biomolecules based on charge differences. Featuring a 4.6 mm internal diameter and a 250 mm length, this column utilizes a NP10 polymeric resin, delivering excellent mechanical and chemical stability even under challenging analytical conditions. Its optimized particle and pore design offer enhanced resolution and reproducibility, making it ideal for applications such as protein characterization, antibody purification, conjugate analysis, and quality control in biopharmaceutical workflows.

This SCX column is well-suited for use in ion exchange chromatography workflows requiring robust and reliable performance. It integrates seamlessly with Agilent HPLC and UHPLC instruments, including 1200 Infinity and 1260 Infinity series systems, as well as a broad range of compatible chromatography platforms. Users in research and industry benefit from its ability to handle complex samples with high throughput and minimal carryover. Related products such as Agilent Bio SAX columns or additional buffer kits can further expand analytical capabilities. This solution is an essential tool for laboratories seeking precise charge variant analysis and efficient biomolecule separations in regulated or research environments.