Agilent, 5190-2436, Agilent Bio SCX, NP10, 4.6 x 50 mm, PEEK

Agilent Bio SCX, NP10, 4.6 x 50 mm, PEEK. A strong cation exchange HPLC column with nonporous particles. Particle size is 10 μm. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio SCX
Column Material: PEEK
Guard Column: No
Hardware: PEEK
Inner Diameter (ID): 4.6 mm
LC Platform: BioInert
Length: 50 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteins
Particle Size: 10 µm
Particle Type: Non-porous
Phase: SCX
Pressure Rating: 275 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio SCX, NP10, 4.6 x 50 mm, PEEK column offers high-resolution cation exchange chromatography for biomolecular analysis. Designed with a 4.6 mm internal diameter and 50 mm length, it utilizes PEEK hardware to ensure robust chemical stability and biocompatibility, minimizing sample interaction and carryover. The column effectively separates proteins, peptides, and other positively charged biomolecules, making it highly suitable for proteomics research, pharmaceutical quality control, and biopharmaceutical development. It performs well in both analytical and micro-preparative workflows.

This strong cation exchange column features a consistent particle size distribution for reproducible retention times and peak shapes. It is widely used for monoclonal antibody characterization, charge variant profiling, and protein pharmaceuticals analysis under non-denaturing conditions. The column is compatible with Agilent 1100 and 1200 Series HPLC systems, InfinityLab LC Series, as well as other standard HPLC and UHPLC instruments utilizing compatible fittings. For optimal performance, it can be paired with Agilent mobile phase additives and guard columns designed for protein separations. This product supports a broad range of biomolecule separations and integrates seamlessly into regulated laboratory environments requiring high throughput and precision.