Agilent, 5190-2440, Agilent Bio SCX, NP10, 2.1 x 50 mm, PEEK

Agilent Bio SCX, NP10, 2.1 x 50 mm, PEEK. A strong cation exchange HPLC column with nonporous particles. Particle size is 10 μm. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio SCX
Column Material: PEEK
Guard Column: No
Hardware: PEEK
Inner Diameter (ID): 2.1 mm
LC Platform: BioInert
Length: 50 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteins
Particle Size: 10 µm
Particle Type: Non-porous
Phase: SCX
Pressure Rating: 275 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio SCX NP10 2.1 x 50 mm PEEK column is designed for robust, high-resolution separation of biomolecules based on charge differences using strong cation exchange (SCX) chromatography. Its NP10 stationary phase provides optimal retention and selectivity for proteins, peptides, and other charged analytes, making it ideal for biopharmaceutical characterization, proteomics studies, and quality control of monoclonal antibodies. The 2.1 mm internal diameter and 50 mm column length facilitate efficient separations with reduced solvent consumption, supporting both analytical and fast screening workflows.

Constructed with PEEK hardware, this column is compatible with bioinert liquid chromatography systems and is highly resistant to corrosive buffers and high-salt mobile phases typically required in SCX analyses. Its dimensions are suited for use with UHPLC and HPLC systems such as Agilent 1260 Infinity II and 1290 Infinity II LC series, as well as comparable platforms from other major manufacturers. Recommended for workflows involving charge variant analysis, peptide mapping, and impurity profiling, this column integrates seamlessly with Agilent’s broader portfolio of biopharmaceutical columns and sample preparation solutions. Reliable batch-to-batch performance ensures reproducible results for demanding research and development applications.