Agilent, 5190-6846, Agilent Bio SEC-3, 100Å, 4.6 x 50 mm, 3 µm, guard

Agilent Bio SEC-3, 100Å, 4.6 x 50 mm, 3 µm, guard. A size exclusion guard column to protect and extend the lifetime of a longer analytical SEC column.

Specifications:
Brand: Agilent Bio SEC-3
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 100 Da
Molecular Weight Upper Limit: 100000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 3 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 100 Å
Pressure Rating: 240 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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Designed for high-resolution size exclusion chromatography of biomolecules, this 4.6 x 50 mm column features 3 µm particles with 100Å pore size, making it ideal for the analysis of proteins, peptides, and other small biomolecules. Frequently used as a guard column, it provides efficient protection for analytical columns by trapping particulates and contaminants, ensuring longer column lifespan and consistent performance. Its robust silica-based design delivers excellent reproducibility and stability, even with repeated use in demanding analytical workflows.

This guard column supports accurate molecular weight determination, protein aggregation studies, and quality control assessments in pharmaceutical, biotechnology, and academic research laboratories. It is fully compatible with Agilent high-performance liquid chromatography systems, including the 1200 Infinity Series, and is also suitable for integration with other leading HPLC and UHPLC platforms. The product performs optimally with corresponding Agilent Bio SEC-3 analytical columns and can be integrated as part of advanced bioseparation workflows in conjunction with Agilent protein and peptide standards.

Optimized for use with aqueous mobile phases, this guard column is a vital component in maintaining system integrity and delivering reliable, reproducible results in critical bioanalytical applications.