Agilent, 671750-902, Poroshell Extend 300 C18, 1.0 x 75 mm, 5 µm

Poroshell Extend 300 C18, 1.0 x 75 mm, 5 µm. A reversed-phase C18 HPLC column with superficially porous particles. The 300-Extend C18 incorporates a unique bidentate silane which allows the column to withstand pH up to 11.5.

Specifications:
Brand: Poroshell 300
Hardware: SS
Inner Diameter (ID): 1.0 mm
LC Platform: Stainless Steel
Length: 75 mm
Maximum Temperature: 40 °C at pH 8-11.560 °C at pH 6-8
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 5 µm
Particle Type: Superficially Porous
Phase: Extend-C18
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Reversed Phase
Shipping Solvent: Methanol/Water
Technique: LC
UNSPSC Code: 41115709
pH Range: 2-11

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The Agilent Poroshell Extend 300 C18 column, sized 1.0 x 75 mm with a 5 micron particle size, is engineered for high-performance liquid chromatography workflows requiring enhanced resolution of large biomolecules and peptides. Utilizing superficially porous particle technology with a 300 angstrom pore size, this column enables efficient separation of high molecular weight compounds such as monoclonal antibodies, oligonucleotides, and protein digests. Its proprietary C18 bonding and robust silica matrix deliver consistent retention and superior peak shape, even under demanding gradients and varying pH conditions. This analytical solution is optimal for peptide mapping, intact protein analysis, and proteomic profiling in pharmaceutical, biotechnological, and academic research laboratories. Compatible with leading Agilent LC systems, including 1100 and 1200 Series, as well as other standard HPLC and UHPLC platforms, it seamlessly integrates into existing laboratory workflows. The column also supports a range of matched Poroshell chemistries, allowing flexibility for method development and optimization. Designed for reproducibility and long column life, it minimizes sample carryover and provides reliable quantitation, making it a cost-effective choice for routine and advanced biomolecular separations.