Agilent, 785775-906, AdvanceBio RP-mAb SB-C8, 2.1 x 100 mm, 3.5 µm

AdvanceBio RP-mAb SB-C8, 2.1 x 100 mm, 3.5 µm. A reversed-phase C8 HPLC column with superficially porous particles and a wide (450 Å) pore size designed for intact or subunit analysis of mAbs. StableBond technology ensures stability at low pH.

Specifications:
Brand: AdvanceBio RP mAb C8
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 100 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: SB-C8
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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The AdvanceBio RP-mAb SB-C8 column offers high-performance reversed-phase liquid chromatography designed specifically for the analysis of monoclonal antibodies and related biologics. Featuring a 2.1 x 100 mm dimension and 3.5 micrometer particle size, this column delivers superior resolution and reproducibility for intact and subunit-level protein characterization. Its stable SB-C8 bonded phase ensures excellent lot-to-lot consistency and durability under demanding method conditions, providing robust separation of large biomolecules while maintaining protein integrity.

This column is ideal for applications such as purity assessment, stability testing, and aggregate analysis in biopharmaceutical research and development settings. It supports efficient method transfer between laboratories and is fully compatible with high-pressure UHPLC and HPLC systems, including Agilent InfinityLab LC series and other leading platforms. The stationary phase chemistry is optimized for high recovery and low adsorption, enabling reliable quantitation and characterization across a range of complex sample matrices.

For best results and streamlined workflows, this column can be integrated with Agilent’s AdvanceBio sample preparation and detection solutions, complementing comprehensive workflows for mAb analysis. Its performance is supported by rigorous quality control, making it a trusted choice for scientists working in analytical and quality control laboratories.