Agilent, 789775-906, AdvanceBio RP-mAb SB-C8, 2.1 x 50 mm, 3.5 µm

AdvanceBio RP-mAb SB-C8, 2.1 x 50 mm, 3.5 µm. A reversed-phase C8 HPLC column with superficially porous particles and a wide (450 Å) pore size designed for intact or subunit analysis of mAbs. StableBond technology ensures stability at low pH.

Specifications:
Brand: AdvanceBio RP mAb C8
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: SB-C8
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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The AdvanceBio RP-mAb SB-C8 column, designed with a 2.1 x 50 mm dimension and 3.5 micron particle size, offers exceptional performance for reversed phase chromatography of monoclonal antibodies and related biologics. Engineered with a stable, rugged C8 bonded phase, this column provides optimal retention and resolution of intact proteins and antibody fragments, making it ideal for in-depth biopharmaceutical characterization, quality control, and stability studies.

Optimized for high throughput and reproducibility, the column delivers sharp, consistent peak shapes even with complex biological matrices. It supports workflows such as verification of antibody integrity, monitoring of product variants, and assessment of product heterogeneity. The robust design ensures excellent pressure tolerance and long-lasting performance, reducing downtime and increasing laboratory efficiency.

This column is fully compatible with Agilent InfinityLab and 1200 Series LC systems, as well as other major UHPLC and HPLC platforms. When used with Agilent AdvanceBio Mobile Phases and other AdvanceBio columns, researchers can achieve enhanced chromatographic performance and streamlined method development. Well suited for use in pharmaceutical, biotechnology, and academic research laboratories, this product enables precise, reproducible analysis critical for therapeutic antibody development and regulatory compliance.