AdvanceBio Gly-X deglycosylation module, 96-ct. Utilizes a novel 5- minute in-solution enzymatic protein deglycosylation (AdvanceBio N-glycanase, PNGaseF).
Specifications:
Count: 96
Equipment & Reagents Provided by User: 96-well Thermocycler or two independent heat blocks, set for 90°C and 50°CThermocycler (Corning THERM-1001, 110 V. THERM-1000, 230 V)
Kit Configuration: Sample Prep Module
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The AdvanceBio Gly-X deglycosylation module offers an efficient, high-throughput solution for N-glycan sample preparation in biopharmaceutical workflows. Supplied as a 96-count format, this module streamlines enzymatic deglycosylation of glycoproteins, delivering rapid and reproducible results suitable for both research and quality control environments. Its design minimizes manual handling while maintaining consistency across samples, making it ideal for laboratories processing large numbers of biotherapeutic or plasma-derived protein samples.
This module is particularly valuable for applications such as glycoprofiling, glycan structural elucidation, and comparability studies of monoclonal antibodies or biosimilars. By enabling reliable removal of N-linked glycans, it supports downstream processes including HILIC-UPLC, LC-MS, and capillary electrophoresis glycan analysis.
Optimized for compatibility with a variety of Agilent AdvanceBio Gly-X kits and consumables, this system integrates seamlessly with Agilent LC and LC-MS platforms, including 1290 Infinity II and 1260 Infinity II systems. Researchers benefit from efficient workflow integration and robust data generation, enabling comprehensive glycan characterization in both discovery and routine testing environments. This module supports cGMP-compliant environments and meets the performance demands of modern biopharma analytics.