Agilent, GX96-401AB, AdvanceBio Gly-X deglycosylation and 2-AB Express labeling module set, 96-ct

AdvanceBio Gly-X deglycosylation and 2-AB Express labeling module set, 96-ct. Utilizes a novel in-solution enzymatic protein deglycosylation followed by on-matrix Express on-matrix labeling of released N-glycans with 2-AB dye, with no prior drydown. With deglycosylation carried out in solution, the method is simple, rapid, and suitable for automation. Includes GX24-100 Gly-X deglycosylation module, GX96-401 Gly-X 2-AB Express labeling module. For cleanup use GX96-402 Gly-X 2-AB Express cleanup module (96-ct).

Specifications:
Application: Flexible, high-throughput format:process 1 to 96 samples
Count: 96
Equipment & Reagents Provided by User: 96-well Thermocycler or two independent heat blocksAcetonitrile (ACN), MS-grade (Fisher A955-4 recommended)DI waterThermocycler (Corning THERM-1001, 110 V. THERM-1000, 230 V)Vacuum manifold (Millipore MSVMHTS00-HTS)Vacuum manifold spacer (GX100, or GX400 Gly-X 2-AB Starter Kit - included free of charge with first Gly-X order, please contact us for details)Vacuum pump (Millipore WP6211560, 110 V. WP6122050, 220 V. Welch WOB-L Pump 2522)
Kit Configuration: Sample Prep Module Set
Label: 2-AB
Technique: LC & LC/MS

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This module set offers a comprehensive solution for rapid and efficient N-glycan sample preparation and fluorescent labeling in high-throughput workflows. Designed for robust deglycosylation and express 2-aminobenzamide labeling, the kit enables researchers to process up to ninety-six samples in parallel, making it ideal for biotherapeutic characterization, quality control, and glycoprofiling studies. The streamlined workflow reduces hands-on time and sample loss, facilitating consistent release and sensitive detection of N-glycans from IgG, monoclonal antibodies, and other glycoproteins.

Optimized for compatibility with Agilent AdvanceBio Glycan Mapping UHPLC columns, as well as LC and LC-MS platforms, the module integrates seamlessly into established analytical pipelines. Applications extend across biopharmaceutical development, biosimilarity assessments, and biomarker discovery, where accurate glycan analysis is critical. Each kit includes ready-to-use reagents for deglycosylation and rapid 2-AB labeling, ensuring reproducible sample preparation with minimal user intervention.

This set can be paired effectively with additional Agilent AdvanceBio sample preparation and consumable products for end-to-end glycan analysis. The user-friendly protocol accelerates sample turnaround, supporting both discovery and regulated laboratory environments with high data quality and reproducibility.