Agilent, PL1212-4201, PLRP-S 300Å, 25 x 25 mm, 20 µm, guard

PLRP-S 300Å, 25 x 25 mm, 20 µm, guard. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 25 mm
LC Platform: Stainless Steel
Length: 25 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: PeptidesPreparative HPLC Columns & Bulk MediaProteins
Particle Size: 20 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 300 Å
Pressure Rating: 103 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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This high-performance guard cartridge is designed for advanced reversed-phase chromatography applications, featuring a 300 angstrom pore size, 25 by 25 millimeter dimensions, and robust 20 micron particle size. Its highly purified polymeric resin delivers exceptional chemical and pH stability, making it ideal for the analysis of large biomolecules such as proteins, peptides, and nucleic acids. Laboratory workflows benefit from consistent retention characteristics and reproducible results, even under harsh mobile phase conditions or elevated temperatures.

This guard cartridge effectively protects analytical and preparative columns by trapping particulates and strongly retained contaminants, thereby extending the service life and performance of your primary column. It is highly suited for biopharmaceutical, proteomics, and biotechnology research where sample integrity and instrument reliability are critical.

Compatible with Agilent PLRP-S columns as well as a range of standard liquid chromatography systems, this guard is a reliable choice for use in UHPLC, HPLC, and FPLC workflows. Integration is straightforward and maintenance is minimal, supporting efficient throughput in demanding laboratory environments. For optimal performance, pair this guard with matched stationary phase columns and consult Agilent’s portfolio of column hardware and consumables for tailored solutions across a variety of analytical and preparative scale separations.