Agilent, PL1980-3250PK, AdvanceBio SEC 120A 1.9um 2.1x150mm PEEK

AdvanceBio SEC 120A 1.9um 2.1x150mm PEEK. A size exclusion column designed for higher resolution and faster separation of protein and peptide aggregates and fragments. PEEK-lined stainless steel hardware offers a metal-free sample flow path.

Specifications:
Brand: AdvanceBio SEC
Guard Column: No
Hardware: PEEK Lined SS
Inner Diameter (ID): 2.1 mm
LC Platform: BioInert
Length: 150 mm
Maximum Temperature: 80 °C (20 to 40 °C recommended)
Molecular Weight Lower Limit: 1000 Da
Molecular Weight Upper Limit: 80000 Da
Particle Size: 1.9 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 120 Å
Pressure Rating: 620 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer/0.02% Sodium azide
Technique: LC & LC/MS
pH Range: 2-8.5

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The AdvanceBio SEC 120A 1.9 μm 2.1 x 150 mm PEEK column is engineered for high-resolution size exclusion chromatography of biomolecules, including monoclonal antibodies, proteins, and large complexes. Featuring 1.9 μm particle technology and a 120 angstrom pore size, this column delivers enhanced resolution, allowing precise molecular weight determination and aggregate analysis. The durable PEEK hardware construction offers excellent chemical resistance and minimizes protein interaction, making it suitable for sensitive biopharmaceutical workflows and environments requiring metal-free operation.

Ideally suited for applications such as characterization of biotherapeutics, purity assessments, and aggregation studies, this column supports method development and quality control in pharmaceutical and biotechnology research laboratories. Its narrow 2.1 mm internal diameter design is optimized for high-efficiency separations with reduced solvent consumption, integrating seamlessly with UHPLC and high-performance LC systems from Agilent and other major vendors. For comprehensive protein analytics, it complements Agilent’s full suite of AdvanceBio columns and consumables. The column’s robust performance ensures reliable reproducibility and accuracy, supporting regulatory compliance and advanced analytics in research, process development, and quality assurance environments.