Cytiva, 17546804, Capto™ SP ImpRes ion exchange chromatography resin

Capto SP ImpRes, 5 L With a high binding capacity and small bead size, Capto™ SP ImpRes strong cation exchanger is a good choice for reliable and robust polishing steps in industrial purification. • High-resolution intermediate purification and polishing resin based on the well-established Capto™ platform with traditional ligands. Smaller particle size compared with Capto™ S. • Flexible process design due to large operational window of flow rates and bed heights. • High throughput purifications easy to optimize and scale-up. • Higher manufacturing productivity enables improved process economy. • Resin fulfills industrial demands for security of supply, robust performance, and regulatory support Designed for large feed volumes Capto™ SP ImpRes is a strong cation exchanger for the high-throughput intermediate purification and polishing steps of a wide range of biomolecules. This chromatography resin is part of an expanded high-resolution platform based on the high-flow agarose Capto™ product line. By combining the high-flow characteristics of Capto™ resin with a small particle size, Capto™ SP ImpRes delivers excellent pressure-flow properties with impressive resolution. The ability to run at higher flow rates and higher bed heights also increases flexibility in process design. Suits large-scale purification processes Capto™ SP ImpRes is a BioProcess™ chromatography resin developed for large-scale purification of biopharmaceutical proteins. Based on the well-established Capto™ base matrix and with traditional ionic group ligands, it provides many opportunities for improved productivity and straightforward process development. Prepacked columns and other formats Capto™ SP ImpRes resin is available in the following formats: Process development scale: prepacked PreDictor™ filter plates , 96-well plates for high-throughput screening or process development. PreDictor™ RoboColumn™ units, miniaturized columns for high-throughput process development. HiScreen™ columns , optimized for method and process development. Validation columns , scale-down columns for robust and reproducible process validation and process development (Tricorn™ format) f (x) columns , precalibrated chromatography column for fast and accurate mechanistic modeling during downstream process development. Lab scale: prepacked for manual purification HiTrap™ columns , for easy use with a syringe, peristaltic pump, or chromatography system. Lab scale: prepacked for automated purification and analysis HiTrap™ columns , for easy use with a syringe, peristaltic pump, or chromatography system. Process characterization: resin kits Process Characterization Kit , designed for studying the potential impact that resin ligand density might have on the process outcome. Process-scale purification: prepacked ReadyToProcess™ columns , 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.