Avantor Guard Cartridges for HPLC & UHPLC Column Protection

Avantor Guard Cartridges are essential accessories designed to protect HPLC and UHPLC columns from particulate contamination and strongly retained compounds.
By capturing impurities before they reach the analytical column, these cartridges help maintain peak integrity, reduce system downtime, and significantly extend column lifespan.
Compatible with a wide range of Avantor chromatography columns, they are ideal for laboratories seeking consistent performance and reliable separation results in demanding analytical workflows.

Key Benefits of Using Avantor Guard Cartridges

Avantor Guard Cartridges are engineered to enhance the performance and durability of your HPLC and UHPLC systems. They offer multiple operational advantages that help protect your investment and improve overall workflow efficiency.

• Effective Column Protection
  Guard cartridges trap particulate matter and impurities before they enter the analytical column, preventing damage and contamination.
• Extended Column Lifespan
  By reducing exposure to harmful substances, they help prolong the service life of expensive chromatography columns.
• Consistent Peak Shape and Separation
  These cartridges preserve chromatographic performance by maintaining optimal flow paths and minimizing peak distortion.
• Easy to Replace and Maintain
  Designed for simple installation and quick replacement, they allow users to maintain system performance with minimal downtime.
• High Compatibility with Avantor Columns
  Each guard cartridge is precisely matched to Avantor’s chromatography columns, ensuring seamless integration and reliable results.

Applications of Avantor Guard Cartridges in Chromatography

Avantor Guard Cartridges are widely used across industries where high-performance liquid chromatography (HPLC and UHPLC) is essential. They provide an added layer of protection in workflows that involve complex or contaminated samples.

• Pharmaceutical Analysis
  Used in quality control and drug development to maintain column performance during repeated runs with challenging matrices.
• Food and Beverage Testing
  Protects columns from food residues and particulates, ensuring accurate detection of additives, contaminants, or nutrients.
• Environmental Monitoring
  Ideal for samples containing dirt, particulates, or unknown compounds that may shorten column life.
• Biotechnology and Life Sciences
  Supports routine and research-based analyses involving biological fluids or complex formulations.
• Routine Chemical Analysis
  A practical solution for labs running daily tests on various sample types, where minimizing maintenance and maximizing consistency are key.

Types of Avantor Guard Cartridges Available

Avantor offers a variety of guard cartridges tailored to different chromatography needs. Each type is designed to match specific analytical columns in both chemistry and dimension, ensuring optimal compatibility and performance.

HPLC Guard Cartridges
Standard-pressure cartridges designed for traditional HPLC workflows, compatible with common stationary phases such as C18, C8, and phenyl.

UHPLC Guard Cartridges
High-pressure cartridges engineered for UHPLC systems, offering low dead volume and high stability under elevated operating pressures.

Prepacked Guard Cartridges
Convenient, ready-to-use cartridges packed with matching stationary phase materials to protect specific analytical columns.

Guard Cartridge Kits with Holders
Bundled solutions that include both cartridges and compatible holders, ideal for first-time setup or system upgrades.

Featured Avantor Guard Cartridges