Avantor HPLC Columns – Accurate, Efficient, and Ready for Your Workflow

Avantor HPLC columns deliver high performance for demanding analytical applications. These columns are designed for accurate and consistent separations. They are widely used in pharmaceutical testing, food analysis, and environmental monitoring. Avantor offers a range of bonded phases and column formats to suit different needs. Each column ensures excellent reproducibility and sharp peak resolution. Whether for routine quality control or complex analysis, Avantor HPLC columns are a trusted choice in laboratories worldwide.

Applications of Avantor HPLC Columns in Modern Analytical Workflows

Avantor HPLC columns are used across a wide range of industries. In pharmaceutical labs, they help separate and quantify active ingredients and impurities. In food testing, they support the analysis of additives, preservatives, and nutrients. Environmental laboratories use them to detect trace levels of pollutants and contaminants. These columns are also suitable for biochemical research, including protein, peptide, and metabolite analysis. With high reproducibility and flexible phase options, Avantor HPLC columns fit both routine and advanced analytical workflows.

Why Choose Avantor HPLC Columns – Performance You Can Trust

Avantor HPLC columns are designed to meet the rigorous demands of analytical laboratories. Their construction and chemistry ensure consistent performance across a variety of applications. Below are the key features that make them a reliable choice for your chromatography workflows:

• High Column Efficiency
  Achieve sharp peak shapes and excellent resolution, even in complex mixtures, for more accurate data interpretation.
• Excellent Reproducibility
  Precision manufacturing ensures consistent performance from column to column and batch to batch.
• Low Bleed and MS Compatibility
  Clean, stable baselines and low background signal make these columns ideal for LC/MS and other sensitive detection methods.
• Broad Solvent and pH Compatibility
  Suitable for a wide range of mobile phase conditions, supporting reversed-phase, normal-phase, and ion exchange techniques.
• Multiple Bonded Phase Options
  Available in C18, C8, CN, NH₂, and more—allowing you to select the optimal chemistry for your analytical goals.

Explore the Different Types of Avantor HPLC Columns

Avantor offers a wide range of HPLC column chemistries to support various analytical techniques. Whether you’re working with polar, non-polar, charged, or size-based separations, there’s a column type designed to meet your needs:

Reversed-Phase Columns (C18, C8, Phenyl, CN)
Ideal for separating non-polar to moderately polar compounds. Commonly used in pharmaceutical, food, and environmental testing.

Normal-Phase Columns (Silica, NH₂)
Suitable for polar analytes that do not retain well on reversed-phase columns. Often used for isomer or sugar separation.

Ion Exchange Columns
Designed for the separation of charged molecules such as amino acids, peptides, and nucleotides. Excellent for bioanalysis and water quality testing.

Size Exclusion Columns (SEC/GFC)
Used for separating molecules based on size, particularly useful in protein analysis and polymer characterization.

Specialty Columns
Avantor also provides niche solutions for chiral separations, method development, or highly specific applications.

FAQ – Choosing and Using Avantor HPLC Columns

1. What bonded phase should I use for pharmaceutical analysis?

C18 is the most widely used bonded phase for pharmaceutical compounds, offering strong retention for non-polar and moderately polar analytes.

2. What type of column should I use for protein or peptide analysis?

For proteins and peptides, size exclusion columns (SEC) or wide-pore reversed-phase columns are recommended. Avantor offers options tailored for biomolecule separations with high recovery and reproducibility.

3. Is method transfer from other brands to Avantor columns possible?

In most cases, yes. Avantor HPLC columns are manufactured to industry standards, making them compatible with common methods and transferable with minimal adjustments.