Avantor Method Development Kit Collection

Avantor Method Development Kits are designed to support fast and effective HPLC and UHPLC method development. Each kit includes multiple columns with different stationary phases.

These kits allow analysts to compare column selectivity, identify the best chemistry for their compounds, and optimize separation conditions with fewer trial-and-error steps.

They are ideal for research labs, pharmaceutical companies, and QA/QC teams looking to develop reliable and reproducible analytical methods.

Why Choose Avantor Method Development Kits

Avantor Method Development Kits offer key advantages for chromatographic method development. They help you test multiple stationary phases quickly and efficiently.

Key benefits include:

• Faster method development
  Evaluate several column chemistries in one run. Save time on column screening.
• Improved selectivity and resolution
  Compare different stationary phases side by side. Find the best match for your analytes.
• Higher reproducibility
  Each column in the kit is manufactured with tight quality control for consistent performance.
• Broad compatibility
  Suitable for most HPLC and UHPLC systems. Work well with reversed-phase methods and common mobile phases.

These kits are a practical choice for labs that need robust and repeatable results in less time.

Applications of Avantor Method Development Kits

Avantor Method Development Kits are widely used in laboratories that need to develop or optimize chromatographic methods. They are suitable for both routine and research-based workflows.

Typical application areas include:

• Pharmaceutical analysis
  Identify the best column for drug substances, impurities, and degradation products.
• Biopharmaceutical development
  Screen conditions for proteins, peptides, and biologics with complex matrices.
• Food and environmental testing
  Separate small molecules such as additives, pesticides, and contaminants.
• Academic and contract research labs
  Accelerate method setup and column selection across a variety of analytes.

These kits help users reduce development time while improving method reliability and accuracy.

How to Choose the Right Method Development Kit

Selecting the right Avantor Method Development Kit depends on your sample type, system, and method goals. The following points can help guide your decision:

1. Know your sample properties

Check the polarity, solubility, and matrix complexity. For non-polar compounds, start with C18 or phenyl phases. For polar analytes, consider CN or polar-embedded phases.

2. Define your separation mode

Use reversed-phase kits for most pharmaceutical or environmental samples. Choose HILIC or normal-phase kits for highly polar compounds.

3. Check your system compatibility

Make sure the column size and pressure limits match your HPLC or UHPLC system. Most kits are compatible with instruments from Agilent, Waters, Shimadzu, and Thermo Fisher.

4. Choose suitable column dimensions

Typical columns come in 150 × 4.6 mm or 100 × 2.1 mm sizes, with particle sizes of 3 µm or 5 µm. Smaller particles give better resolution but require higher pressure.

5. Consider regulatory requirements

If you're developing methods for GMP or QC labs, choose kits that include phases meeting USP or ICH guidelines. Batch traceability and COA availability are also important.

These steps help ensure that the kit you choose supports fast, accurate, and reproducible method development.

Regulatory Readiness for QC and Validation

Avantor Method Development Kits support regulatory-compliant method development in pharmaceutical and biotech labs.

Key features that support compliance include:

• High lot-to-lot consistency
  Columns are manufactured under strict quality controls to ensure reproducible results.
• COA and batch traceability
  Each column comes with a certificate of analysis. Lot numbers are clearly labeled for full traceability.
• USP and ICH guideline support
  Many stationary phases are suitable for methods aligned with USP <621> and ICH Q2(R1) recommendations.
• Validated for robustness and repeatability
  Kits help users develop methods that meet precision and robustness requirements for regulated environments.

These features make Avantor kits a reliable choice for QA/QC workflows and method validation projects.

Related Collections You May Be Interested In

If you're exploring Avantor Method Development Kits, the following collections may also meet your analytical needs:

• Avantor HPLC Columns
  A wide range of individual columns for routine analysis, available in multiple stationary phases and dimensions.
• Reversed-Phase Columns
  Ideal for small molecule separations in pharmaceutical, food safety, and environmental applications.
• Guard Cartridges
  Extend column life and protect your main columns from sample contamination.

These collections work well with method development workflows and can help you streamline your full testing process.