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    Corning Transwell Permeable Supports Collection

    54 products

    Corning Transwell® permeable supports are advanced cell culture inserts designed to enable in vitro modeling of physiological barriers and cell interactions. These versatile permeable supports feature a microporous membrane, allowing researchers to separate cell populations while maintaining the exchange of nutrients, signals, and compounds between compartments.

    Widely used in migration and invasion assays, drug transport studies, co-culture systems, and air–liquid interface (ALI) culture models, Corning Transwell inserts provide reliable performance for diverse applications in life sciences and pharmaceutical research. Their precision-engineered membranes and broad range of formats make them an essential tool for cell biology, toxicology, and disease modeling workflows.

    Key Applications of Corning Transwell® Permeable Supports

    Corning Transwell® permeable supports are engineered to support a wide range of cell-based assays and advanced in vitro models. These cell culture inserts are essential tools for simulating complex biological processes, enabling scientists to analyze cellular behaviors and barrier functions with precision.

    Corning Transwell Permeable Supports
    Cell Migration & Invasion Assays
    Transwell supports are widely used to assess the migratory and invasive capacity of cancer, immune, or stem cells, helping researchers understand mechanisms of cell movement across a barrier.
    Drug Transport & Permeability Studies
    By mimicking physiological barriers, Transwell inserts allow precise measurement of compound permeability, drug absorption, and transport across epithelial or endothelial cell layers.
    Cell Polarity & Barrier Function Analysis
    Transwell permeable supports facilitate the study of cell polarization and tight junction formation, providing insights into tissue integrity and function in vitro.
    Co-Culture & Signal Transduction
    The unique design enables physical separation of different cell types while allowing paracrine signaling, making it ideal for co-culture experiments and studies of cell-cell communication.
    Air–Liquid Interface (ALI) Culture
    Transwell systems support ALI culture, critical for respiratory research and differentiation of airway epithelial cells, closely replicating in vivo conditions.

    Core Features and Benefits of Corning Transwell® Permeable Supports

    Corning Transwell® permeable supports are engineered with precision to meet the diverse needs of cell culture, barrier function assays, and drug transport studies. Their innovative design and high-quality materials ensure reliable and reproducible results across a variety of research applications.

    Key features and advantages include:

    • Advanced Microporous Membrane Structure
      Each insert features a precisely manufactured microporous membrane, facilitating the exchange of nutrients, metabolites, and signaling molecules while maintaining separation between cell populations.

    • Multiple Membrane Options
      Available in both polycarbonate (PC) and polyester (PET) materials, allowing researchers to select the optimal membrane for their specific assay or cell type requirements.

    • Wide Range of Pore Sizes
      Choose from several pore size options (0.4 µm, 3.0 µm, 8.0 µm, and more), supporting applications from tight barrier formation to cell migration and invasion studies.

    • Flexible Formats for Every Workflow
      Offered in single-well, 6-well, 12-well, 24-well, and high-throughput 96-well configurations, these inserts are compatible with manual and automated laboratory workflows.

    • Sterile, Ready-to-Use Design
      All Corning Transwell cell culture inserts are supplied sterile, minimizing contamination risk and ensuring convenience for cell culture experiments.

    • Robust Quality and Consistency
      Manufactured under stringent quality standards, providing consistent membrane thickness, uniform pore size distribution, and reliable performance batch after batch.

    How to Select the Right Corning Transwell® Permeable Support

    Choosing the appropriate Corning Transwell® permeable support is essential for achieving reliable and meaningful results in cell culture and assay workflows. The selection should consider membrane material, pore size, and format based on specific experimental requirements, such as migration assays, barrier formation, or co-culture studies.

    The table below provides a practical guide to help researchers match Transwell insert features to common applications:

    Application Recommended Pore Size Membrane Material Typical Format Notes
    Cell Migration & Invasion 3.0 µm, 8.0 µm Polycarbonate (PC) 24-well, Single Insert Allows cell passage and quantification
    Drug Transport & Permeability 0.4 µm Polyester (PET) 12-well, 24-well Ideal for Caco-2 and MDCK permeability assays
    Cell Polarity & Barrier Function 0.4 µm PET, PC 6-well, 12-well Supports tight junction and TEER measurement
    Co-Culture Systems 0.4 µm, 3.0 µm PET, PC 24-well, 96-well Enables paracrine signaling and cell contact
    Air–Liquid Interface (ALI) Culture 0.4 µm PET 6-well, 12-well Supports respiratory and epithelial models
    High-Throughput Screening (HTS) 0.4 µm, 3.0 µm PET, PC 24-well, 96-well Compatible with automation and multiwell plates

    Selecting the right Transwell insert ensures optimal assay performance, data accuracy, and experimental reproducibility across various life science and pharmaceutical research settings.

    Featured Corning Transwell® Permeable Supports: SKUs and Specifications

    Corning offers a comprehensive range of Transwell® permeable supports, tailored to meet the needs of various cell culture applications. Each product is precisely engineered with specific pore sizes, membrane materials, and well formats to optimize performance in migration assays, permeability studies, and co-culture experiments. The table below highlights some of the most popular and widely used SKUs, making it easy for researchers to compare and select the right insert for their experimental requirements.

    Corning Transwell Pore Polycarbonate
    SKU Well Format Insert Diameter Membrane Material Pore Size (µm) Recommended Applications
    3413 24-well 6.5 mm Polyester (PET) 0.4 Drug permeability, barrier function, ALI
    3422 24-well 6.5 mm Polycarbonate (PC) 3.0 Migration and invasion assays
    3470 Single insert 24 mm Polycarbonate (PC) 8.0 High-throughput cell migration, large cells
    3450 6-well 24 mm Polyester (PET) 0.4 Cell polarity, barrier studies, ALI culture
    3378 24-well HTS 6.5 mm Polyester (PET) 0.4 Automation, drug transport, screening
    3385 96-well HTS 6.5 mm Polycarbonate (PC) 3.0 High-throughput migration, co-culture
    3472 Single insert 12 mm Polycarbonate (PC) 0.4 TEER, barrier integrity, small-scale assays

    For detailed product information, custom formats, or additional pore size options, you can contact us via email.

    Related Corning Collections and Compatible Laboratory Accessories

    Enhance the performance and versatility of Corning Transwell® permeable supports by pairing them with these recommended laboratory consumables and accessories. Each collection is designed to streamline cell culture workflows and ensure reliable results across a variety of applications.

    Corning Assay Microplates
    Specially designed microplates for high-throughput screening, ELISA, and fluorescence/luminescence assays, ideal for use alongside HTS Transwell formats.

    Corning Pipettes & Pipette Tips
    Precision pipettes and sterile tips for accurate sample transfer, reagent addition, and maintenance of sterile conditions during cell culture and assay preparation.

    Corning Reservoir and Receiver Plates
    Reservoir and receiver plates compatible with multiwell Transwell formats, enabling efficient liquid handling and collection of basolateral samples.

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