Sartorius Chromatography Solutions for Bioprocessing Excellence

Sartorius stands at the forefront of chromatography innovation, delivering scalable purification solutions for bioprocessing, research, and pharmaceutical production. The Sartorius Chromatography portfolio brings together state-of-the-art membrane chromatography, advanced multi-column continuous systems, and high-performance HPLC and column technologies. These solutions are designed to streamline your downstream workflows, accelerate process development, and maximize purity and yield at every scale.

Whether you are developing monoclonal antibodies, producing viral vectors for gene therapy, or scaling up vaccine manufacturing, Sartorius provides the flexibility, efficiency, and reliability required for modern purification challenges. By integrating cutting-edge technologies such as Sartobind® membrane adsorbers and Resolute® BioSMB multi-column platforms, you gain access to tools that redefine productivity and reduce process bottlenecks.

Applications & Benefits of Sartorius Chromatography

Sartorius chromatography solutions are trusted globally across a wide spectrum of applications, from R&D labs to full-scale biomanufacturing. Key application areas include:

• Antibody and Protein Purification: Achieve high recovery rates and process throughput for mAbs, recombinant proteins, and enzymes.
• Viral Vector and Vaccine Production: Streamline downstream processing for AAV, lentivirus, adenovirus, and vaccine candidates, with robust viral clearance and high-capacity options.
• Bioprocess Development: Accelerate method development and process intensification for new biologics, cell therapies, and gene therapy products.
• Continuous and Batch Manufacturing: Support both innovative continuous purification strategies and established batch workflows.

Compared to traditional resin-based chromatography, Sartorius technologies offer several distinct advantages:

By selecting Sartorius, you gain operational flexibility, cost efficiency, and reliable, validated performance for demanding downstream purification tasks.

Product Categories: Membrane, Continuous, Columns & HPLC

Sartorius offers a comprehensive range of chromatography solutions tailored to address diverse purification needs, from lab-scale R&D to GMP manufacturing:

Membrane Chromatography (Sartobind®)

Sartobind® membrane adsorbers enable ultra-fast, high-capacity purification of proteins, viruses, and plasmids. Their convective flow properties reduce process time from hours to minutes, making them ideal for polishing, viral clearance, and impurity removal. Sartobind® is available in scalable capsule formats and large-scale cassettes, ensuring consistent results from screening to production.

Multi-Column Continuous Chromatography (Resolute® BioSMB)

The Resolute® BioSMB platform delivers true continuous purification, maximizing productivity while minimizing resin usage. Available in models suitable for process development through to large-volume commercial manufacturing, BioSMB allows seamless transition from batch to continuous, supporting process intensification and cost reduction in both mAb and novel modality workflows.

Chromatography Columns & Batch Systems

Sartorius provides a wide selection of pre-packed and empty chromatography columns (DAC columns), compatible with most leading media. These columns are optimized for plug-and-play integration with Sartorius or third-party systems, ensuring robust performance for capture, intermediate, and polishing steps. Batch chromatography systems are available for both single-use and multi-use needs, supporting flexible scale-up.

Preparative HPLC & Purification Kits

For small molecule, peptide, and oligonucleotide purification, Sartorius offers preparative HPLC systems and ready-to-use purification kits. These platforms deliver high-resolution separations and reproducible results, enabling efficient method development and pilot-scale runs for a wide variety of molecules.

Featured Products: Key Models & Specifications

Below is a selection of Sartorius chromatography products, with SKUs referenced from the official Sartorius portfolio. For the latest product codes and specifications, always refer to the Sartorius website.

Selection & Procurement Guide (FAQ)

Q1: Should I choose membrane chromatography or traditional resin chromatography for my application?

A: Membrane chromatography (Sartobind®) is ideal when you require rapid processing, high flow rates, or need to remove trace impurities and viruses. Resin chromatography remains preferred for high-capacity capture steps. Many modern workflows integrate both for optimal efficiency.

Q2: When is continuous chromatography (Resolute® BioSMB) the right choice?

A: Choose continuous multi-column chromatography if you want to intensify your process, reduce resin consumption, and maximize throughput. It’s particularly beneficial for large-scale mAb or vaccine manufacturing.

Q3: How do I select the right Sartobind® membrane format?

A: Select based on your process scale—nano and mini capsules for R&D, mid-sized for pilot, and large cassettes (e.g., 1.0 L STIC PA) for commercial manufacturing. All formats offer scalable performance and validated virus removal.

Why Choose Sartorius & How to Buy

Sartorius chromatography technologies are trusted by leading biopharmaceutical companies and research institutions worldwide, recognized for reliability, innovation, and robust process performance. By choosing Sartorius, you unlock scalable solutions that keep pace with modern purification challenges and regulatory requirements.

For expert consultation, up-to-date product information, or to request a quote, contact iRight—your trusted partner for Sartorius chromatography products. Our team offers comprehensive support for selection, procurement, and technical integration to ensure you achieve outstanding results in every purification step.