Agilent, 5190-2428, Agilent Bio SCX, NP5, 4.6 x 50 mm, PEEK

Agilent Bio SCX, NP5, 4.6 x 50 mm, PEEK. A strong cation exchange HPLC column with nonporous particles. Particle size is 5 μm. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio SCX
Column Material: PEEK
Guard Column: Yes
Hardware: PEEK
Inner Diameter (ID): 4.6 mm
LC Platform: BioInert
Length: 50 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteins
Particle Size: 5 µm
Particle Type: Non-porous
Phase: SCX
Pressure Rating: 413 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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Designed for high-performance separation of biomolecules, the Agilent Bio SCX, NP5, 4.6 x 50 mm, PEEK column is ideal for ion-exchange chromatography of proteins and peptides. Featuring strong cation-exchange (SCX) media and a robust PEEK (polyether ether ketone) housing, this column offers exceptional chemical resistance and minimizes protein adsorption, enabling sensitive, reproducible results. The NP5 particle technology ensures high resolution and efficient separation even at elevated flow rates, making it suitable for both routine quantitation and advanced proteomic studies.

The column is optimized for demanding research and quality control applications, including protein characterization, charge variant analysis of monoclonal antibodies, and peptide mapping. It is fully compatible with Agilent HPLC and UHPLC systems, as well as other major chromatography platforms, offering flexibility for diverse laboratory workflows. The 4.6 mm internal diameter and 50 mm length deliver rapid analysis and high throughput without compromising performance.

This SCX column pairs well with Agilent’s full range of bio-inert instruments and accessories, such as bio-inert LC systems and compatible guard columns. Reliable and easy to install, it supports consistent results for pharmaceutical, biopharmaceutical, and academic research laboratories seeking precision in biomolecule separation.