Agilent, 5190-2434, Agilent Bio SCX, NP10, 4 x 10 mm, guard

Agilent Bio SCX, NP10, 4 x 10 mm, guard. A strong cation exchange HPLC guard column with nonporous particles. Particle size is 10 μm. Nonporous particles are best for efficient mass transfer and high resolution separations.

Specifications:
Brand: Agilent Bio SCX
Column Material: Stainless Steel
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 4 mm
LC Platform: Stainless Steel
Length: 10 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteins
Particle Size: 10 µm
Particle Type: Non-porous
Phase: SCX
Pressure Rating: 275 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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Designed for robust performance in the protection of analytical columns, this guard cartridge features strong cation exchange (SCX) properties with NP10 media, contained within a compact 4 x 10 mm format. It ensures the removal of particulate contaminants and strongly binding substances from biological samples prior to chromatography, significantly increasing the lifespan and maintaining the performance of high-value analytical columns. This guard is particularly suited for the analysis and characterization of proteins, peptides, and other biomolecules in biopharmaceutical research, quality control, and academic laboratories.

Its SCX chemistry provides optimal retention and resolution for compounds with positive charges, making it an ideal choice for workflows involving ion exchange chromatography. It seamlessly integrates with compatible Agilent Bio SCX analytical columns, ensuring consistent, reproducible results. The guard cartridge is easily installed into most standard column hardware, thereby supporting flexible use in various liquid chromatography systems, including Agilent 1100, 1200 Infinity, 1260 Infinity, and 1290 Infinity series instrumentation.

Utilizing this accessory not only protects downstream analytical components but also enhances overall system reliability and data integrity in demanding research and quality assurance environments. It is recommended for laboratories seeking to maintain high throughput and reliable separations in bioanalysis applications.