Agilent, 761973-902, ZORBAX Extend 300 C18, 4.6 x 100 mm, 3.5 µm

ZORBAX Extend 300 C18, 4.6 x 100 mm, 3.5 µm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. The 300-Extend C18 chemistry incorporates a unique bidentate silane which allows the column to withstand pH up to 11.5.

Specifications:
Brand: ZORBAX
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 100 mm
Maximum Temperature: 40 °C at pH 8-11.560 °C at pH 6-8
Part Number Application Domain: Biopharma
Part Number Application: Monoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 3.5 µm
Particle Type: Fully Porous
Phase: Extend-C18
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115709
pH Range: 2-11

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The ZORBAX Extend 300 C18 column features a 4.6 x 100 mm dimension and 3.5 micron particle size, designed for robust and efficient reversed-phase liquid chromatography. Its wide pore, 300 angstrom design is optimized for the separation of larger biomolecules such as peptides, proteins, nucleic acids, and their fragments, making it an ideal choice for biopharmaceutical and proteomics research. The stable C18 bonded phase provides excellent retention, selectivity, and reproducibility across a broad pH range, allowing for method flexibility and compatibility with demanding sample matrices. This column supports high sensitivity and resolution, even for analytes prone to peak tailing or secondary interactions. It integrates seamlessly with a variety of HPLC and UHPLC systems, including Agilent InfinityLab and 1100, 1200, and 1260 Series instruments. The ZORBAX Extend 300 C18 column is suitable for use in applications such as peptide mapping, protein characterization, oligonucleotide analysis, and quality control testing. For optimal performance, it can be paired with Agilent guard columns and compatible solvents to maximize column lifetime and sample throughput. This product is a trusted solution for laboratories seeking reliable and high-performance bioseparations.