Agilent, 765750-902, ZORBAX Extend 300 C18, 2.1 x 50 mm, 3.5 µm

ZORBAX Extend 300 C18, 2.1 x 50 mm, 3.5 µm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. The 300-Extend C18 chemistry incorporates a unique bidentate silane which allows the column to withstand pH up to 11.5.

Specifications:
Brand: ZORBAX
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 40 °C at pH 8-11.560 °C at pH 6-8
Part Number Application Domain: Biopharma
Part Number Application: Monoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 3.5 µm
Particle Type: Fully Porous
Phase: Extend-C18
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115709
pH Range: 2-11

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The ZORBAX Extend 300 C18 column in a 2.1 x 50 mm format with 3.5 µm particle size is designed for advanced reversed-phase high-performance liquid chromatography separations. Featuring an extended pH stability range, this column is ideally suited for the analysis of peptides, proteins, and small biomolecules, accommodating both low and high pH mobile phases without compromising column longevity or performance. Its wide 300 Å pore size enhances mass transfer for larger molecules, improving resolution and peak capacity in both qualitative and quantitative workflows.

This column is commonly used in pharmaceutical research, proteomics, biopharmaceutical characterization, and quality control labs seeking reliable separation of complex biological samples. Its short column length and narrow internal diameter promote rapid analyses with minimal solvent usage, making it compatible with UHPLC and fast LC systems. The column is optimized for use with Agilent 1100, 1200, 1260, and 1290 Infinity LC systems, as well as other industry-standard HPLC/UHPLC instruments. ZORBAX Extend technology ensures ruggedness and reproducibility across numerous injection cycles, supporting high-throughput workflows. It can be paired with ZORBAX guard columns and a range of Agilent sample preparation products to further enhance performance and method robustness in demanding analytical environments.