Agilent, 765973-902, ZORBAX Extend 300 C18, 4.6 x 50 mm, 3.5 µm

ZORBAX Extend 300 C18, 4.6 x 50 mm, 3.5 µm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. The 300-Extend C18 chemistry incorporates a unique bidentate silane which allows the column to withstand pH up to 11.5.

Specifications:
Brand: ZORBAX
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 40 °C at pH 8-11.560 °C at pH 6-8
Part Number Application Domain: Biopharma
Part Number Application: Monoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 3.5 µm
Particle Type: Fully Porous
Phase: Extend-C18
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115709
pH Range: 2-11

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The ZORBAX Extend 300 C18 column features a 4.6 x 50 mm dimension and 3.5 micron particle size, making it ideal for high-performance liquid chromatography applications that demand reliable separation of complex biological molecules. Designed with an extended-pH stability, this column effectively separates peptides, proteins, and large biomolecules, even under high-pH mobile phase conditions. Its wide 300 angstrom pore size enhances interaction with larger analytes, resulting in improved resolution and reproducibility for bioanalysis, pharmaceutical research, and biotherapeutic characterization.

This column is a preferred choice for laboratories engaged in protein mapping, peptide mapping, and sample purification workflows. It excels in reversed-phase chromatography for the analysis of monoclonal antibodies and other biopharmaceutical compounds. Compatible with a wide range of Agilent HPLC and UHPLC systems, it integrates seamlessly into existing laboratory setups, ensuring robust and reproducible performance. The column also aligns with Agilent ZORBAX guard columns and consumables for extended operational life and reliable results. Researchers benefit from its low backpressure and consistent peak shape, which contribute to accurate quantitation and increased laboratory throughput in regulated environments.