Agilent, 795975-904, AdvanceBio RP-mAb C4, 4.6 x 100 mm, 3.5 µm

AdvanceBio RP-mAb C4, 4.6 x 100 mm, 3.5 µm. A reversed-phase C4 HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins for intact or subunit analysis.

Specifications:
Brand: AdvanceBio RP mAb C4
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 100 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: C4
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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Engineered for high-performance reversed-phase chromatography, this C4 column with 4.6 x 100 mm dimensions and 3.5 micron particle size is optimized for the separation, characterization, and analysis of monoclonal antibodies and related large biomolecules. The column delivers excellent resolution and peak capacity for intact protein analysis, making it a reliable choice for biopharmaceutical development, quality control, and in-depth research workflows.

Advanced silica bonding and proprietary end-capping technologies ensure consistent retention and enhanced stability, supporting robust operation across a broad range of mobile phases and sample types. This solution is ideal for laboratories investigating therapeutic monoclonal antibodies, antibody-drug conjugates, and complex protein therapeutics, providing essential insights into identity, purity, and potential modifications.

Compatible with Agilent HPLC and UHPLC systems, it also integrates seamlessly with many industry-standard liquid chromatography platforms. When used with Agilent AdvanceBio sample preparation and detection products, it helps enable comprehensive workflow integration from sample to result. The column’s reliable reproducibility and high lot-to-lot consistency support confident method transfer and regulated environment requirements, making it a trusted tool for leading biopharma and research laboratories.