Agilent, 797775-904, AdvanceBio RP-mAb C4, 2.1 x 75 mm, 3.5 µm

AdvanceBio RP-mAb C4, 2.1 x 75 mm, 3.5 µm. A reversed-phase C4 HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins for intact or subunit analysis.

Specifications:
Brand: AdvanceBio RP mAb C4
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 75 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: C4
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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Designed for high-resolution reversed-phase chromatography, this column features a 2.1 x 75 mm dimension and 3.5 micron particle size, making it ideal for the robust separation and analysis of monoclonal antibodies and related biologics. Utilizing advanced C4 bonded silica, it provides excellent performance in intact protein and subunit mapping workflows, supporting both native and denatured state analyses. The superior lot-to-lot reproducibility ensures consistent retention times and reliable quantitation, facilitating routine quality control and advanced research applications. Optimized for compatibility with most high-performance liquid chromatography HPLC and ultra-high performance liquid chromatography UHPLC systems, this column integrates seamlessly with leading Agilent LC instruments, such as the 1260 Infinity II and 1290 Infinity II series, as well as comparable systems from other major manufacturers. It is particularly suitable for biopharmaceutical development, characterization of therapeutic antibodies, and detailed protein impurity profiling. Supporting related consumables and mobile phases are available within Agilent's AdvanceBio family to streamline workflows and enhance method robustness. This product is trusted by scientists for its durability, reproducibility, and ability to deliver precise results across critical biotherapeutic research and quality assurance environments.